Ihn Kyung. Jang, et.al., Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20498059

Ihn Kyung. Jang, et.al., Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Grb2<tm1.1Hua>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4462852

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD8-positive, alpha-beta T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008079I129C57BL6Grb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0Grb2tm11HuaTgLckcre1Jtak
• abnormal T cell differentiation_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(DO11.10)10Dlo/0,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0002145I129C57BL6Grb2tm11HuaGrb2tm11HuaTgDO111010Dlo0TgLckcre1Jtak0TgLckcre1JtakGrb2tm11HuaTgDO111010Dlo
• increased double-positive T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0005091I129C57BL6C57BL6JDBA2JGrb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0TgTcraHYTcrbHY71Vbo0Grb2tm11HuaTgTcraHYTcrbHY71VboTgLckcre1Jtak
• decreased CD8-positive, alpha-beta T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0008079I129C57BL6C57BL6JDBA2JGrb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0TgTcraHYTcrbHY71Vbo0Grb2tm11HuaTgTcraHYTcrbHY71VboTgLckcre1Jtak
• decreased CD4-positive, alpha beta T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008075I129C57BL6Grb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0Grb2tm11HuaTgLckcre1Jtak
• decreased CD4-positive, alpha beta T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(DO11.10)10Dlo/0,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008075I129C57BL6Grb2tm11HuaGrb2tm11HuaTgDO111010Dlo0TgLckcre1Jtak0TgLckcre1JtakGrb2tm11HuaTgDO111010Dlo
• abnormal T cell differentiation_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0002145I129C57BL6Grb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0Grb2tm11HuaTgLckcre1Jtak
• decreased CD4-positive, alpha beta T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0008075I129C57BL6C57BL6JDBA2JGrb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0TgTcraHYTcrbHY71Vbo0Grb2tm11HuaTgTcraHYTcrbHY71VboTgLckcre1Jtak
• increased CD8-positive, alpha-beta T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0008078I129C57BL6C57BL6JDBA2JGrb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0TgTcraHYTcrbHY71Vbo0Grb2tm11HuaTgTcraHYTcrbHY71VboTgLckcre1Jtak
• decreased double-positive T cell number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0005092I129C57BL6Grb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0Grb2tm11HuaTgLckcre1Jtak
• decreased thymocyte number_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000715I129C57BL6Grb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0Grb2tm11HuaTgLckcre1Jtak
• abnormal T cell differentiation_Grb2<tm1.1Hua>/Grb2<tm1.1Hua>,Tg(Lck-cre)1Jtak/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0002145I129C57BL6C57BL6JDBA2JGrb2tm11HuaGrb2tm11HuaTgLckcre1Jtak0TgTcraHYTcrbHY71Vbo0Grb2tm11HuaTgTcraHYTcrbHY71VboTgLckcre1Jtak

class

http://purl.org/net/cito/citesAsAuthority

• Grb2<tm1.1Hua>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4462852

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12227
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12227