Markus. Kroeber, et.al., Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma., Human molecular genetics, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/20538882

Markus. Kroeber, et.al., Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma., Human molecular genetics, 2010, 19

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• anterior iris synechia_Pax6<tm1Pgr>/Pax6<+>
  http://metadb.riken.jp/0011481I129S1Sv129X1SvJPax6tm1PgrPax6Pax6Pax6tm1Pgr
• microphthalmia_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001297I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• ocular hypertension_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0005258I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• abnormal iris stroma morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)2Pgr/0
  http://metadb.riken.jp/0005208I129S1Sv129X1SvJPax6tm2PgrPax6TgPax6creGFP2Pgr0Pax6tm2PgrPax6TgPax6creGFP2Pgr
• abnormal corneal stroma morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0005300I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• fused cornea and lens_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001307I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• abnormal optic nerve morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001330I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• optic nerve degeneration_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0006219I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• abnormal iridocorneal angle_Pax6<tm1Pgr>/Pax6<+>
  http://metadb.riken.jp/0004221I129S1Sv129X1SvJPax6tm1PgrPax6Pax6Pax6tm1Pgr
• absent Schlemm's canal_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0004226I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• abnormal iridocorneal angle_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0004221I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• small lens_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001306I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• abnormal eye anterior chamber morphology_Pax6<tm1Pgr>/Pax6<+>
  http://metadb.riken.jp/0005205I129S1Sv129X1SvJPax6tm1PgrPax6Pax6Pax6tm1Pgr
• optic nerve hypoplasia_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0006221I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• anterior iris synechia_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0011481I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• absent trabecular meshwork_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0004224I129S1Sv129X1SvJFVBPax6tm2PgrPax6TgPax6creGFP1Pgr0Pax6TgPax6creGFP1PgrPax6tm2Pgr
• fused cornea and lens_Pax6<tm1Pgr>/Pax6<+>
  http://metadb.riken.jp/0001307I129S1Sv129X1SvJPax6tm1PgrPax6Pax6Pax6tm1Pgr