Urmila. Santanam, et.al., Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20566844

Urmila. Santanam, et.al., Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro
  http://metadb.riken.jp/db/mgi_rdf/MGI:4820820

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro
  http://metadb.riken.jp/db/mgi_rdf/MGI:4820820

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• spleen hyperplasia_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0,Tg(Igh-V186.2-TCL1A)3Cro/0
  http://metadb.riken.jp/0000693IC3HC57BL6FVBNTgIghMir29aMir29b1hrGFPCro0TgIghV1862TCL1A3Cro0TgIghMir29aMir29b1hrGFPCroTgIghV1862TCL1A3Cro
• decreased IgG2a level_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0008496FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• increased B-1a cell number_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0008167FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• decreased IgG2b level_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0008497FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• increased B cell proliferation_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0005154FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• abnormal spleen morphology_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0000689FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• decreased IgG1 level_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0008495FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• increased chronic lymphocytic leukemia incidence_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0010337FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• enlarged spleen_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0000691FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• increased chronic lymphocytic leukemia incidence_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0,Tg(Igh-V186.2-TCL1A)3Cro/0
  http://metadb.riken.jp/0010337IC3HC57BL6FVBNTgIghMir29aMir29b1hrGFPCro0TgIghV1862TCL1A3Cro0TgIghMir29aMir29b1hrGFPCroTgIghV1862TCL1A3Cro
• increased B-1a cell number_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0,Tg(Igh-V186.2-TCL1A)3Cro/0
  http://metadb.riken.jp/0008167IC3HC57BL6FVBNTgIghMir29aMir29b1hrGFPCro0TgIghV1862TCL1A3Cro0TgIghMir29aMir29b1hrGFPCroTgIghV1862TCL1A3Cro
• spleen hyperplasia_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0000693FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• abnormal B cell physiology_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0002459FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro
• abnormal lymphopoiesis_Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
  http://metadb.riken.jp/0002401FVBNTgIghMir29aMir29b1hrGFPCroTgIghMir29aMir29b1hrGFPCro0TgIghMir29aMir29b1hrGFPCro