Leonardo. Morsut, et.al., Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo., Development (Cambridge, England), 2010, 137

http://rdf.ncbi.nlm.nih.gov/pubmed/20573697

Leonardo. Morsut, et.al., Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo., Development (Cambridge, England), 2010, 137

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trim33<tm1.2Los>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830323
• Trim33<tm1.1Los>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830322
• Smad4<tm1.1Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830314

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal endoderm development_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001685I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• decreased embryo size_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0001698I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• embryonic lethality between implantation and somite formation, complete penetrance_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0011096I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• abnormal embryo development_Smad4<tm1Rdp>/Smad4<tm1.1Rdp>,Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001672I129SSvEv129S2SvPasC57BL6SJLSmad4tm1RdpSmad4tm11RdpTrim33tm11LosTrim33tm12LosTgCAGcre13Miya0TgCAGcre13MiyaTrim33tm12LosSmad4tm11RdpTrim33tm11LosSmad4tm1Rdp
• abnormal brain development_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000913I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• absent extraembryonic ectoderm_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0002583I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• abnormal anterior visceral endoderm morphology_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0008533I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• decreased embryo size_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001698I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• expanded anterior visceral endoderm_Nodal<tm1Rob>/Nodal<+>,Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0012160I129SSvEv129S2SvPasC57BL6Nodaltm1RobNodalTrim33tm12LosTrim33tm12LosNodaltm1RobNodalTrim33tm12Los
• absent anterior visceral endoderm_Smad4<tm1Rdp>/Smad4<tm1.1Rdp>,Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0012159I129SSvEv129S2SvPasC57BL6SJLSmad4tm1RdpSmad4tm11RdpTrim33tm11LosTrim33tm12LosTgCAGcre13Miya0TgCAGcre13MiyaTrim33tm12LosSmad4tm11RdpTrim33tm11LosSmad4tm1Rdp
• abnormal anterior visceral endoderm morphology_Tg(CAG-cre)13Miya/0,Trim33<tm1.1Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0008533I129129S2SvPasC57BL6SJLTgCAGcre13Miya0Trim33tm11LosTrim33tm12LosTgCAGcre13MiyaTrim33tm12LosTrim33tm11Los
• abnormal embryonic-extraembryonic boundary morphology_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0003890I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• abnormal primitive node morphology_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004066I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• failure of primitive streak formation_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0001693I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• absent anterior visceral endoderm_Smad4<tm1Rdp>/Smad4<tm1.1Rdp>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0012159I129SSvEv129S2SvPasC57BL6SJLSmad4tm1RdpSmad4tm11RdpTgCAGcre13Miya0Smad4tm1RdpSmad4tm11RdpTgCAGcre13Miya
• abnormal embryo development_Smad4<tm1Rdp>/Smad4<tm1.1Rdp>,Tg(CAG-cre)13Miya/0
  http://metadb.riken.jp/0001672I129SSvEv129S2SvPasC57BL6SJLSmad4tm1RdpSmad4tm11RdpTgCAGcre13Miya0Smad4tm1RdpSmad4tm11RdpTgCAGcre13Miya
• abnormal developmental patterning_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0002084I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• abnormal embryo development_Tg(CAG-cre)13Miya/0,Trim33<tm1.1Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0001672I129129S2SvPasC57BL6SJLTgCAGcre13Miya0Trim33tm11LosTrim33tm12LosTgCAGcre13MiyaTrim33tm12LosTrim33tm11Los
• abnormal mesendoderm development_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0009266I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• incomplete rostral neuropore closure_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000928I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• embryonic lethality, incomplete penetrance_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011102I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• abnormal primitive streak elongation_Trim33<tm1.1Los>/Trim33<tm1.2Los>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0012685I129S2SvPasC57BL6CBASJLTrim33tm11LosTrim33tm12LosTgSox2cre1Amc0TgSox2cre1AmcTrim33tm12LosTrim33tm11Los
• abnormal proamniotic cavity morphology_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0011197I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los
• abnormal mesoderm development_Trim33<tm1.2Los>/Trim33<tm1.2Los>
  http://metadb.riken.jp/0001680I129S2SvPasC57BL6SJLTrim33tm12LosTrim33tm12LosTrim33tm12Los

class

http://purl.org/net/cito/citesAsAuthority

• Trim33<tm1.2Los>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830323
• Trim33<tm1.1Los>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830322
• Smad4<tm1.1Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830314

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD04230
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04230
• CD03905
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03905
• CD07437
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07437
• CD20066
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20066
• CD07450
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07450