Erica. Marchlik, et.al., Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality., Journal of leukocyte biology, 2010, 88

http://rdf.ncbi.nlm.nih.gov/pubmed/20651301

Erica. Marchlik, et.al., Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality., Journal of leukocyte biology, 2010, 88

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tbk1<tm1.1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4847640
• Tbk1<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4847639

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal inflammatory response_Tbk1<tm1.1Lex>/Tbk1<+>
  http://metadb.riken.jp/0001845I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1Tbk1tm11LexTbk1
• abnormal inflammatory response_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0001845I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased tumor necrosis factor secretion_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008560I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased susceptibility to bacterial infection induced morbidity/mortality_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0009788I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased susceptibility to endotoxin shock_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008735I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• prenatal lethality, incomplete penetrance_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0011101I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• hyperkeratosis_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0001242I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• decreased eosinophil cell number_Tbk1<tm1.1Lex>/Tbk1<+>
  http://metadb.riken.jp/0005012I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1Tbk1tm11LexTbk1
• increased interleukin-6 secretion_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008705I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• skin hyperplasia_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0001214I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased circulating interleukin-6 level_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008596I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased circulating interleukin-1 beta level_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008641I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• decreased interferon-beta secretion_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008565I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• lymphoid hyperplasia_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0000688I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• decreased NK T cell number_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008040I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased NK T cell number_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008039I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased monocyte cell number_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0000220I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• postnatal lethality, complete penetrance_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0011085B6129S5Tbk1tm11LexTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• skin inflammation_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0004947I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased spleen weight_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0004952I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• abnormal cytokine level_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008713I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• dermal hyperplasia_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0004971I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased circulating interleukin-10 level_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008593I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• disheveled coat_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0001511I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• abnormal hair cycle anagen phase_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008858I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased IgA level_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0002495I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• decreased basophil cell number_Tbk1<tm1.1Lex>/Tbk1<+>
  http://metadb.riken.jp/0002607I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1Tbk1tm11LexTbk1
• sparse hair_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0000416I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• skin edema_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0001786I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• abnormal cytokine secretion_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0003009I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• increased circulating tumor necrosis factor level_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0008553I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex
• abnormal skin morphology_Tbk1<tm1.1Lex>/Tbk1<tm1.1Lex>
  http://metadb.riken.jp/0002060I129S4SvJae129S5SvEvBrdTbk1tm11LexTbk1tm11LexTbk1tm11Lex

class

http://purl.org/net/cito/citesAsAuthority

• Tbk1<tm1.1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4847640
• Tbk1<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4847639