Manisha C. Yadav, et.al., Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcification., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, 26

http://rdf.ncbi.nlm.nih.gov/pubmed/20684022

Manisha C. Yadav, et.al., Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcification., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, 26

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Phospho1<m1Jlm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5049904

class

http://purl.org/net/cito/citesAsAuthority

• Phospho1<m1Jlm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5049904

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased bone mineral density_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000062IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• scoliosis_Alpl<tm1Jlm>/Alpl<+>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000161I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlplPhospho1m1JlmPhospho1m1JlmAlplPhospho1m1JlmAlpltm1Jlm
• bowed tibia_Alpl<tm1Jlm>/Alpl<+>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0004358I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlplPhospho1m1JlmPhospho1m1JlmAlplPhospho1m1JlmAlpltm1Jlm
• decreased compact bone thickness_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000135IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• bowed humerus_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0004373IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• bowed tibia_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0004358IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• prenatal lethality, incomplete penetrance_Alpl<tm1Jlm>/Alpl<+>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0011101I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlplPhospho1m1JlmPhospho1m1JlmAlplPhospho1m1JlmAlpltm1Jlm
• abnormal rib morphology_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000150IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• decreased bone mineral density_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000063IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• abnormal skeleton morphology_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0005508IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• bowed femur_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0004371IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• decreased body weight_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0001262IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• abnormal compact bone morphology_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0003797IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• fragile skeleton_Alpl<tm1Jlm>/Alpl<+>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000061I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlplPhospho1m1JlmPhospho1m1JlmAlplPhospho1m1JlmAlpltm1Jlm
• abnormal bone structure_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0003795IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• fragile skeleton_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000061IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• abnormal clavicle morphology_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0005298IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• decreased body size_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0001265IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• short tibia_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0002764IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• bowed radius_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0004374IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• increased circulating phosphate level_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0001566IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• bowed ulna_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0004361IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• increased bone trabecula number_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0010868IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• short femur_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0003109IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• decreased fluid intake_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0011942IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• scoliosis_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000161IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• abnormal trabecular bone morphology_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0000130IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• abnormal chondrocyte physiology_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0009780IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• decreased food intake_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0011940IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• decreased bone ossification_Alpl<tm1Jlm>/Alpl<+>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0020040I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlplPhospho1m1JlmPhospho1m1JlmAlplPhospho1m1JlmAlpltm1Jlm
• postnatal growth retardation_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0001732IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• decreased bone mineralization_Alpl<tm1Jlm>/Alpl<+>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0020137I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlplPhospho1m1JlmPhospho1m1JlmAlplPhospho1m1JlmAlpltm1Jlm
• abnormal long bone morphology_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0003723IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• bowed fibula_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0004372IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• failure of bone ossification_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0008274IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm
• abnormal bone mineralization_Alpl<tm1Jlm>/Alpl<tm1Jlm>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0002896I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlpltm1JlmPhospho1m1JlmPhospho1m1JlmAlpltm1JlmPhospho1m1Jlm
• lethality throughout fetal growth and development, complete penetrance_Alpl<tm1Jlm>/Alpl<tm1Jlm>,Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0011099I129S2SvPasC3HeBFeJC57BL6Alpltm1JlmAlpltm1JlmPhospho1m1JlmPhospho1m1JlmAlpltm1JlmPhospho1m1Jlm
• osteomalacia_Phospho1<m1Jlm>/Phospho1<m1Jlm>
  http://metadb.riken.jp/0009445IC3HeBFeJC57BL6Phospho1m1JlmPhospho1m1JlmPhospho1m1Jlm