Mayank. Verma, et.al., Flt-1 haploinsufficiency ameliorates muscular dystrophy phenotype by developmentally increased vasculature in mdx mice., Human molecular genetics, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/20705734

Mayank. Verma, et.al., Flt-1 haploinsufficiency ameliorates muscular dystrophy phenotype by developmentally increased vasculature in mdx mice., Human molecular genetics, 2010, 19

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• extended life span_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>,Utrn<tm1Jrs>/Utrn<tm1Jrs>
  http://metadb.riken.jp/0001661I129S1Sv129X1SvJC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Utrntm1JrsUtrntm1JrsFlt1Dmdmdx5CvFlt1tm1JrtUtrntm1Jrs
• abnormal muscle development_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0000733IC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Flt1Dmdmdx5CvFlt1tm1Jrt
• abnormal muscle contractility_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>
  http://metadb.riken.jp/0005620B6RosCgDmdmdx5CvJDmdmdx5CvDmdmdx5CvDmdmdx5Cv
• abnormal skeletal muscle fiber morphology_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0003084IC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Flt1Dmdmdx5CvFlt1tm1Jrt
• abnormal blood circulation_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0002128IC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Flt1Dmdmdx5CvFlt1tm1Jrt
• abnormal blood vessel morphology_Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0001614NSFlt1tm1JrtFlt1Flt1Flt1tm1Jrt
• abnormal skeletal muscle fiber size_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0009398IC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Flt1Dmdmdx5CvFlt1tm1Jrt
• increased variability of skeletal muscle fiber size_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>
  http://metadb.riken.jp/0009403B6RosCgDmdmdx5CvJDmdmdx5CvDmdmdx5CvDmdmdx5Cv
• increased satellite cell number_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>
  http://metadb.riken.jp/0000730B6RosCgDmdmdx5CvJDmdmdx5CvDmdmdx5CvDmdmdx5Cv
• increased angiogenesis_Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0005601NSFlt1tm1JrtFlt1Flt1Flt1tm1Jrt
• increased body weight_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>,Utrn<tm1Jrs>/Utrn<tm1Jrs>
  http://metadb.riken.jp/0001260I129S1Sv129X1SvJC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Utrntm1JrsUtrntm1JrsFlt1Dmdmdx5CvFlt1tm1JrtUtrntm1Jrs
• centrally nucleated skeletal muscle fibers_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>
  http://metadb.riken.jp/0009404B6RosCgDmdmdx5CvJDmdmdx5CvDmdmdx5CvDmdmdx5Cv
• increased capillary density_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0020330IC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Flt1Dmdmdx5CvFlt1tm1Jrt
• centrally nucleated skeletal muscle fibers_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>,Utrn<tm1Jrs>/Utrn<tm1Jrs>
  http://metadb.riken.jp/0009404I129S1Sv129X1SvJC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Utrntm1JrsUtrntm1JrsFlt1Dmdmdx5CvFlt1tm1JrtUtrntm1Jrs
• abnormal blood circulation_Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0002128NSFlt1tm1JrtFlt1Flt1Flt1tm1Jrt
• abnormal muscle contractility_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0005620IC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Flt1Dmdmdx5CvFlt1tm1Jrt
• increased satellite cell number_Dmd<mdx-5Cv>/Dmd<mdx-5Cv>,Flt1<tm1Jrt>/Flt1<+>
  http://metadb.riken.jp/0000730IC3HAC57BL6RosDmdmdx5CvDmdmdx5CvFlt1tm1JrtFlt1Flt1Dmdmdx5CvFlt1tm1Jrt

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD41754
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD41754