Beth A. Firulli, et.al., Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability., Developmental dynamics : an official publication of the American Association of Anatomists, 2010, 239

http://rdf.ncbi.nlm.nih.gov/pubmed/20737509

Beth A. Firulli, et.al., Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability., Developmental dynamics : an official publication of the American Association of Anatomists, 2010, 239

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4843970
• Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4843975

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cardiac outflow tract development_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0006126NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• abnormal interventricular septum morphology_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0000281NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• abnormal cardiovascular system morphology_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>,Hand2<tm1Dsr>/Hand2<tm1Dsr>
  http://metadb.riken.jp/0002127I129S7SvEvBrdHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand2tm1DsrHand2tm1DsrHand2tm1DsrHand1tm21Hand1Abfi
• abnormal neural tube morphology_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0002151NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• abnormal rostral-caudal axis patterning_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>,Hand2<tm1Dsr>/Hand2<tm1Dsr>
  http://metadb.riken.jp/0005221I129S7SvEvBrdHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand2tm1DsrHand2tm1DsrHand2tm1DsrHand1tm21Hand1Abfi
• abnormal mesoderm development_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0001680NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• decreased embryo size_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>,Hand2<tm1Dsr>/Hand2<tm1Dsr>
  http://metadb.riken.jp/0001698I129S7SvEvBrdHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand2tm1DsrHand2tm1DsrHand2tm1DsrHand1tm21Hand1Abfi
• abnormal cardiac outflow tract development_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0006126NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• thin ventricular wall_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0000280NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• abnormal rostral-caudal axis patterning_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0005221NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• decreased embryo size_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0001698NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• abnormal cardiovascular system morphology_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0002127NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• enlarged allantois_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0004556NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• abnormal heart morphology_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0000266NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• abnormal heart septum morphology_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0006113NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• abnormal visceral yolk sac morphology_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0001718NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• enlarged heart_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0000274NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• dilated heart_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0004937NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• embryonic lethality during organogenesis, complete penetrance_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0011098NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• embryonic lethality during organogenesis, incomplete penetrance_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0011108NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• abnormal myocardial trabeculae morphology_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0002189NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• hemopericardium_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0005244NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• decreased cell proliferation_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0000352NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• thin ventricular wall_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>,Hand2<tm1Dsr>/Hand2<tm1Dsr>
  http://metadb.riken.jp/0000280I129S7SvEvBrdHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand2tm1DsrHand2tm1DsrHand2tm1DsrHand1tm21Hand1Abfi
• decreased cell proliferation_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0000352NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• abnormal embryo development_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0001672NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• abnormal craniofacial morphology_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0000428NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• impaired placental function_Hand1<tm2(Hand1)Abfi>/Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/0006372NSHand1tm2Hand1AbfiHand1tm2Hand1AbfiHand1tm2Hand1Abfi
• abnormal limb bud morphology_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0005650NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi
• abnormal embryo turning_Hand1<tm2.1(Hand1)Abfi>/Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/0001700NSHand1tm21Hand1AbfiHand1tm21Hand1AbfiHand1tm21Hand1Abfi

class

http://purl.org/net/cito/citesAsAuthority

• Hand1<tm2(Hand1)Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4843970
• Hand1<tm2.1(Hand1)Abfi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4843975

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD00644
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00644
• CD04595
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04595
• CD14342
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD14342
• CD39610
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39610
• CD10788
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10788
• CD26160
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD26160
• CD00475
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00475