Mark E. Hatley, et.al., Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21., Cancer cell, 2010, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/20832755

Mark E. Hatley, et.al., Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21., Cancer cell, 2010, 18

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mir21a<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4881915
• Tg(CAG-Mir21,-EGFP)#Eno
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317720

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Kras<tm3Tyj>/Kras<+>,Tg(CAG-Mir21,-EGFP)#Eno/0
  http://metadb.riken.jp/0002083I129S4SvJaeC3HC57BL6Krastm3TyjKrasTgCAGMir21EGFPEno0TgCAGMir21EGFPEnoKrastm3TyjKras
• decreased lung tumor incidence_Kras<tm3Tyj>/Kras<+>,Mir21a<tm1.1Eno>/Mir21a<tm1.1Eno>
  http://metadb.riken.jp/0010267I129SSvEv129S4SvJaeC57BL6Krastm3TyjKrasMir21atm11EnoMir21atm11EnoKrasMir21atm11EnoKrastm3Tyj
• increased lung non-small cell carcinoma incidence_Kras<tm3Tyj>/Kras<+>,Tg(CAG-Mir21,-EGFP)#Eno/0
  http://metadb.riken.jp/0008716I129S4SvJaeC3HC57BL6Krastm3TyjKrasTgCAGMir21EGFPEno0TgCAGMir21EGFPEnoKrastm3TyjKras
• increased lung adenoma incidence_Kras<tm3Tyj>/Kras<+>,Mir21a<tm1.1Eno>/Mir21a<tm1.1Eno>
  http://metadb.riken.jp/0002048I129SSvEv129S4SvJaeC57BL6Krastm3TyjKrasMir21atm11EnoMir21atm11EnoKrasMir21atm11EnoKrastm3Tyj
• lung epithelium hyperplasia_Kras<tm3Tyj>/Kras<+>,Mir21a<tm1.1Eno>/Mir21a<tm1.1Eno>
  http://metadb.riken.jp/0010945I129SSvEv129S4SvJaeC57BL6Krastm3TyjKrasMir21atm11EnoMir21atm11EnoKrasMir21atm11EnoKrastm3Tyj
• increased lung tumor incidence_Kras<tm3Tyj>/Kras<+>,Tg(CAG-Mir21,-EGFP)#Eno/0
  http://metadb.riken.jp/0008014I129S4SvJaeC3HC57BL6Krastm3TyjKrasTgCAGMir21EGFPEno0TgCAGMir21EGFPEnoKrastm3TyjKras
• increased tumor growth/size_Kras<tm3Tyj>/Kras<+>,Tg(CAG-Mir21,-EGFP)#Eno/0
  http://metadb.riken.jp/0003721I129S4SvJaeC3HC57BL6Krastm3TyjKrasTgCAGMir21EGFPEno0TgCAGMir21EGFPEnoKrastm3TyjKras
• decreased tumor incidence_Kras<tm3Tyj>/Kras<+>,Tg(CAG-Mir21,-EGFP)#Eno/0
  http://metadb.riken.jp/0002052I129S4SvJaeC3HC57BL6Krastm3TyjKrasTgCAGMir21EGFPEno0TgCAGMir21EGFPEnoKrastm3TyjKras
• decreased tumor incidence_Kras<tm3Tyj>/Kras<+>,Mir21a<tm1.1Eno>/Mir21a<tm1.1Eno>
  http://metadb.riken.jp/0002052I129SSvEv129S4SvJaeC57BL6Krastm3TyjKrasMir21atm11EnoMir21atm11EnoKrasMir21atm11EnoKrastm3Tyj
• decreased tumor growth/size_Kras<tm3Tyj>/Kras<+>,Mir21a<tm1.1Eno>/Mir21a<tm1.1Eno>
  http://metadb.riken.jp/0003447I129SSvEv129S4SvJaeC57BL6Krastm3TyjKrasMir21atm11EnoMir21atm11EnoKrasMir21atm11EnoKrastm3Tyj
• increased T cell derived lymphoma incidence_Kras<tm3Tyj>/Kras<+>,Mir21a<tm1.1Eno>/Mir21a<tm1.1Eno>
  http://metadb.riken.jp/0002024I129SSvEv129S4SvJaeC57BL6Krastm3TyjKrasMir21atm11EnoMir21atm11EnoKrasMir21atm11EnoKrastm3Tyj

class

http://purl.org/net/cito/citesAsAuthority

• Mir21a<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4881915
• Tg(CAG-Mir21,-EGFP)#Eno
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317720