Ingela. Vikstrom, et.al., Mcl-1 is essential for germinal center formation and B cell memory., Science (New York, N.Y.), 2010, 330

http://rdf.ncbi.nlm.nih.gov/pubmed/20929728

Ingela. Vikstrom, et.al., Mcl-1 is essential for germinal center formation and B cell memory., Science (New York, N.Y.), 2010, 330

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mcl1<tm1Dmta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4840274

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent germinal center B cells_Mcl1<tm1Dmta>/Mcl1<tm1Dmta>,Tg(Aicda-cre)9Mbu/0
  http://metadb.riken.jp/0008179B6CgMcl1tm1DmtaTgAicdacre9MbuMcl1tm1DmtaMcl1tm1DmtaTgAicdacre9Mbu0TgAicdacre9MbuMcl1tm1Dmta
• decreased naive B cell number_Mcl1<tm1Dmta>/Mcl1<tm1Dmta>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008185B6CgMcl1tm1DmtaGtROSA26Sortm9creESR1ArteMcl1tm1DmtaMcl1tm1DmtaGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorGtROSA26Sortm9creESR1ArteMcl1tm1Dmta
• decreased germinal center B cell number_Mcl1<tm1Dmta>/Mcl1<+>,Tg(Aicda-cre)9Mbu/0
  http://metadb.riken.jp/0008178B6CgMcl1tm1DmtaTgAicdacre9MbuMcl1tm1DmtaMcl1TgAicdacre9Mbu0Mcl1tm1DmtaTgAicdacre9MbuMcl1
• decreased germinal center B cell number_Mcl1<tm1Dmta>/Mcl1<+>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008178B6CgMcl1tm1DmtaGtROSA26Sortm9creESR1ArteMcl1tm1DmtaMcl1GtROSA26Sortm9creESR1ArteGtROSA26SorMcl1tm1DmtaGtROSA26Sortm9creESR1ArteGtROSA26SorMcl1
• absent memory B cells_Mcl1<tm1Dmta>/Mcl1<tm1Dmta>,Tg(Aicda-cre)9Mbu/0
  http://metadb.riken.jp/0008094B6CgMcl1tm1DmtaTgAicdacre9MbuMcl1tm1DmtaMcl1tm1DmtaTgAicdacre9Mbu0TgAicdacre9MbuMcl1tm1Dmta
• absent germinal center B cells_Mcl1<tm1Dmta>/Mcl1<tm1Dmta>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008179B6CgMcl1tm1DmtaGtROSA26Sortm9creESR1ArteMcl1tm1DmtaMcl1tm1DmtaGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorGtROSA26Sortm9creESR1ArteMcl1tm1Dmta
• decreased memory B cell number_Mcl1<tm1Dmta>/Mcl1<+>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008729B6CgMcl1tm1DmtaGtROSA26Sortm9creESR1ArteMcl1tm1DmtaMcl1GtROSA26Sortm9creESR1ArteGtROSA26SorMcl1tm1DmtaGtROSA26Sortm9creESR1ArteGtROSA26SorMcl1
• decreased memory B cell number_Mcl1<tm1Dmta>/Mcl1<+>,Tg(Aicda-cre)9Mbu/0
  http://metadb.riken.jp/0008729B6CgMcl1tm1DmtaTgAicdacre9MbuMcl1tm1DmtaMcl1TgAicdacre9Mbu0Mcl1tm1DmtaTgAicdacre9MbuMcl1
• absent memory B cells_Mcl1<tm1Dmta>/Mcl1<tm1Dmta>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008094B6CgMcl1tm1DmtaGtROSA26Sortm9creESR1ArteMcl1tm1DmtaMcl1tm1DmtaGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorGtROSA26Sortm9creESR1ArteMcl1tm1Dmta
• abnormal B cell differentiation_Mcl1<tm1Dmta>/Mcl1<tm1Dmta>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002144B6CgMcl1tm1DmtaGtROSA26Sortm9creESR1ArteMcl1tm1DmtaMcl1tm1DmtaGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorGtROSA26Sortm9creESR1ArteMcl1tm1Dmta
• decreased IgG1 level_Bcl2l1<tm1Dlo>/Bcl2l1<tm1.1Mam>,Tg(Aicda-cre)9Mbu/0
  http://metadb.riken.jp/0008495B6CgBcl2l1tm1DloBcl2l1tm11MamTgAicdacre9MbuBcl2l1tm1DloBcl2l1tm11MamTgAicdacre9Mbu0TgAicdacre9MbuBcl2l1tm1DloBcl2l1tm11Mam
• decreased IgG1 level_Mcl1<tm1Dmta>/Mcl1<tm1Dmta>,Tg(Aicda-cre)9Mbu/0
  http://metadb.riken.jp/0008495B6CgMcl1tm1DmtaTgAicdacre9MbuMcl1tm1DmtaMcl1tm1DmtaTgAicdacre9Mbu0TgAicdacre9MbuMcl1tm1Dmta

class

http://purl.org/net/cito/citesAsAuthority

• Mcl1<tm1Dmta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4840274

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03108
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03108
• CD04015
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04015