Zhao. Chen, et.al., Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene., Cancer research, 2010, 70

http://rdf.ncbi.nlm.nih.gov/pubmed/20952506

Zhao. Chen, et.al., Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene., Cancer research, 2010, 70

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm1(tetO-EML4/ALK)Kkw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5527336

class

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm1(tetO-EML4/ALK)Kkw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5527336

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased lung tumor incidence_Col1a1<tm1(tetO-EML4/ALK)Kkw>/Col1a1<+>,Tg(Scgb1a1-rtTA)1Jaw/0
  http://metadb.riken.jp/0008014I129C57BL6Col1a1tm1tetOEML4ALKKkwCol1a1TgScgb1a1rtTA1Jaw0TgScgb1a1rtTA1JawCol1a1tm1tetOEML4ALKKkwCol1a1
• altered tumor pathology_Col1a1<tm1(tetO-EML4/ALK)Kkw>/Col1a1<+>,Tg(Scgb1a1-rtTA)1Jaw/0
  http://metadb.riken.jp/0010639I129C57BL6Col1a1tm1tetOEML4ALKKkwCol1a1TgScgb1a1rtTA1Jaw0TgScgb1a1rtTA1JawCol1a1tm1tetOEML4ALKKkwCol1a1
• premature death_Col1a1<tm1(tetO-EML4/ALK)Kkw>/Col1a1<+>,Tg(Scgb1a1-rtTA)1Jaw/0
  http://metadb.riken.jp/0002083I129C57BL6Col1a1tm1tetOEML4ALKKkwCol1a1TgScgb1a1rtTA1Jaw0TgScgb1a1rtTA1JawCol1a1tm1tetOEML4ALKKkwCol1a1
• increased lung carcinoma incidence_Col1a1<tm1(tetO-EML4/ALK)Kkw>/Col1a1<+>,Tg(Scgb1a1-rtTA)1Jaw/0
  http://metadb.riken.jp/0008714I129C57BL6Col1a1tm1tetOEML4ALKKkwCol1a1TgScgb1a1rtTA1Jaw0TgScgb1a1rtTA1JawCol1a1tm1tetOEML4ALKKkwCol1a1
• weight loss_Col1a1<tm1(tetO-EML4/ALK)Kkw>/Col1a1<+>,Tg(Scgb1a1-rtTA)1Jaw/0
  http://metadb.riken.jp/0001263I129C57BL6Col1a1tm1tetOEML4ALKKkwCol1a1TgScgb1a1rtTA1Jaw0TgScgb1a1rtTA1JawCol1a1tm1tetOEML4ALKKkwCol1a1