David P. Harris, et.al., Requirement for class II phosphoinositide 3-kinase C2alpha in maintenance of glomerular structure and function., Molecular and cellular biology, 2011, 31

http://rdf.ncbi.nlm.nih.gov/pubmed/20974805

David P. Harris, et.al., Requirement for class II phosphoinositide 3-kinase C2alpha in maintenance of glomerular structure and function., Molecular and cellular biology, 2011, 31

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thrombocytosis_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005505I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased hemoglobin content_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002874I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased creatinine clearance_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005558I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• polyuria_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0001762I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased circulating phosphate level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0001566I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased monocyte cell number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0000220I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• expanded mesangial matrix_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0011353I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased urine protein level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002962I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased circulating potassium level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005627I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased circulating cholesterol level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005178I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• postnatal growth retardation_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0001732I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• enlarged spleen_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0000691I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased hematocrit_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0000208I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• abnormal kidney morphology_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002135I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• small kidney_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002989I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased circulating creatinine level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005553I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• abnormal blood homeostasis_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0009642I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased body weight_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0001262I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased neutrophil cell number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0000219I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• glomerulonephritis_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002743I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased body size_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0001265I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased mean platelet volume_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002599I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased erythrocyte cell number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002875I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased CD8-positive, alpha-beta T cell number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0008078I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased B cell number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005014I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased anti-double stranded DNA antibody level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0004762I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• premature death_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002083I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• kidney failure_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0003606I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• glomerulosclerosis_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005264I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased granulocyte number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0000322I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased blood urea nitrogen level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005565I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased IgG level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002493I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased total body fat amount_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0010025I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased circulating alkaline phosphatase level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002968I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased lean body mass_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0003961I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased IgM level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002494I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased CD4-positive, alpha beta T cell number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0008074I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• podocyte foot process effacement_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0008140I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased IgA level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0002495I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• abnormal podocyte morphology_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005326I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• decreased circulating bilirubin level_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005635I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• abnormal renal glomerulus morphology_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0005325I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• pale kidney_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0004969I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex
• increased leukocyte cell number_Pik3c2a<Gt(OST288105)Lex>/Pik3c2a<Gt(OST288105)Lex>
  http://metadb.riken.jp/0000218I129S5SvEvBrdC57BL6JPik3c2aGtOST288105LexPik3c2aGtOST288105LexPik3c2aGtOST288105Lex

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD18372
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18372