Laure. Gambardella, et.al., PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis., Science signaling, 2010, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/20978237

Laure. Gambardella, et.al., PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis., Science signaling, 2010, 3

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Arap3<tm1.1Sve>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428753
• Arap3<tm2.1Sve>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428755
• Arap3<tm1.2Sve>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428754

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal vitelline vasculature morphology_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0003229I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• embryonic lethality during organogenesis, complete penetrance_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011098I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• pallor_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0003717I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• embryonic growth arrest_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0001730I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• decreased placental labyrinth size_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0011521I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• excessive folding of visceral yolk sac_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011205I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• decreased embryo size_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0001698I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• abnormal angiogenesis_Arap3<tm1.2Sve>/Arap3<+>
  http://metadb.riken.jp/0000260I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3Arap3Arap3tm12Sve
• embryonic growth arrest_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001730I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal developmental vascular remodeling_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0009577I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal placenta vasculature_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003231I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• excessive folding of visceral yolk sac_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0011205I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• embryonic lethality during organogenesis, complete penetrance_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011098I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• pallor_Arap3<tm2.1Sve>/Arap3<tm2.1Sve>
  http://metadb.riken.jp/0003717I129P2OlaHsdArap3tm21SveArap3tm21SveArap3tm21Sve
• abnormal vitelline vascular remodeling_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0004076I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• abnormal brain vasculature morphology_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0004950I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal brain vasculature morphology_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0004950I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• decreased embryo size_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001698I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal developmental vascular remodeling_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0009577I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• embryonic lethality during organogenesis, complete penetrance_Arap3<tm2.1Sve>/Arap3<tm2.1Sve>
  http://metadb.riken.jp/0011098I129P2OlaHsdArap3tm21SveArap3tm21SveArap3tm21Sve
• decreased embryo size_Arap3<tm2.1Sve>/Arap3<tm2.1Sve>
  http://metadb.riken.jp/0001698I129P2OlaHsdArap3tm21SveArap3tm21SveArap3tm21Sve
• excessive folding of visceral yolk sac_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011205I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• abnormal vitelline vasculature morphology_Arap3<tm2.1Sve>/Arap3<tm2.1Sve>
  http://metadb.riken.jp/0003229I129P2OlaHsdArap3tm21SveArap3tm21SveArap3tm21Sve
• decreased placental labyrinth size_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011521I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• pale yolk sac_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001722I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• embryonic growth arrest_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001730I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• abnormal placenta labyrinth morphology_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001716I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal placenta vasculature_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003231I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal brain vasculature morphology_Arap3<tm2.1Sve>/Arap3<tm2.1Sve>
  http://metadb.riken.jp/0004950I129P2OlaHsdArap3tm21SveArap3tm21SveArap3tm21Sve
• decreased placental labyrinth size_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011521I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• abnormal placenta labyrinth morphology_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001716I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• abnormal brain vasculature morphology_Arap3<tm1.2Sve>/Arap3<+>
  http://metadb.riken.jp/0004950I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3Arap3Arap3tm12Sve
• decreased embryo size_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001698I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• abnormal angiogenesis_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0000260I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• pallor_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003717I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal vascular branching morphogenesis_Arap3<tm2.1Sve>/Arap3<tm2.1Sve>
  http://metadb.riken.jp/0003227I129P2OlaHsdArap3tm21SveArap3tm21SveArap3tm21Sve
• pallor_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003717I129P2OlaHsdBALBcJC57BL6CBASJLArap3tm11SveArap3tm12SveTgSox2cre1Amc0Arap3tm11SveArap3tm12SveTgSox2cre1Amc
• abnormal vitelline vasculature morphology_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003229I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• pale yolk sac_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0001722I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa
• abnormal placenta labyrinth morphology_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0001716I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• abnormal placenta vasculature_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0003231I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• excessive folding of visceral yolk sac_Arap3<tm2.1Sve>/Arap3<tm2.1Sve>
  http://metadb.riken.jp/0011205I129P2OlaHsdArap3tm21SveArap3tm21SveArap3tm21Sve
• embryonic lethality during organogenesis, complete penetrance_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0011098I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• abnormal vascular branching morphogenesis_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0003227I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• pale yolk sac_Arap3<tm1.2Sve>/Arap3<tm1.2Sve>
  http://metadb.riken.jp/0001722I129P2OlaHsdBALBcJC57BL6SJLArap3tm12SveArap3tm12SveArap3tm12Sve
• abnormal vitelline vascular remodeling_Arap3<tm1.1Sve>/Arap3<tm1.2Sve>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0004076I129P2OlaHsdBALBcJC57BL6SJLArap3tm11SveArap3tm12SveTgTekcre1Ywa0Arap3tm12SveArap3tm11SveTgTekcre1Ywa

class

http://purl.org/net/cito/citesAsAuthority

• Arap3<tm1.1Sve>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428753
• Arap3<tm2.1Sve>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428755
• Arap3<tm1.2Sve>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428754

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD05191
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05191