Kathryn M. Shinnick, et.al., Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice., The Journal of clinical investigation, 2010, 120

http://rdf.ncbi.nlm.nih.gov/pubmed/21041951

Kathryn M. Shinnick, et.al., Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice., The Journal of clinical investigation, 2010, 120

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gmnn<tm1Tjm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4999617

class

http://purl.org/net/cito/citesAsAuthority

• Gmnn<tm1Tjm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4999617

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased leukocyte cell number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000221I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• decreased erythrocyte cell number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002875I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• abnormal spleen red pulp morphology_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002356I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• abnormal proerythroblast morphology_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002416I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• abnormal common lymphocyte progenitor cell morphology_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008249I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• absent erythroid progenitor cell_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000216I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• decreased hematopoietic stem cell proliferation_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0011903I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• increased hematopoietic stem cell number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004809I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• decreased neutrophil cell number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000222I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• abnormal megakaryocyte progenitor cell morphology_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002413I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• abnormal bone marrow cell physiology_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0009278I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• no abnormal phenotype detected_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>
  http://metadb.riken.jp/0002169I129SvC57BL6C57BL6JGmnntm1TjmGmnntm1TjmGmnntm1Tjm
• anemia_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001577I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• premature death_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• increased megakaryocyte cell number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008254I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• abnormal bone marrow cell morphology/development_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002398I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• decreased bone marrow cell number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000333I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• reticulocytopenia_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008941I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• decreased granulocyte number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000334I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• abnormal common myeloid progenitor cell morphology_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0006410I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• decreased erythroid progenitor cell number_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008973I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• thrombocytosis_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005505I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn
• increased circulating erythropoietin level_Gmnn<tm1Tjm>/Gmnn<tm1Tjm>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0011285I129SvC57BL6C57BL6JCBAGmnntm1TjmGmnntm1TjmTgMx1cre1Cgn0Gmnntm1TjmTgMx1cre1Cgn

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD04338
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04338