Joanna. Giza, et.al., Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/21048139

Joanna. Giza, et.al., Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mapk8ip2<tm1Gol>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867720
• Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867721

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• reduced AMPA-mediated synaptic currents_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0011003129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• abnormal excitatory postsynaptic currents_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0002910129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• abnormal social investigation_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0001360129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• thin cerebellar molecular layer_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0000890129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• enhanced NMDA-mediated synaptic currents_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0003234129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• reduced fertility_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0001921129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• abnormal Purkinje cell morphology_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0000877129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• impaired coordination_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0001405129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• decreased anxiety-related response_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0001364129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• decreased exploration in new environment_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0001417129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• abnormal Purkinje cell dendrite morphology_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0008572129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• decreased synaptic glutamate release_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0004495129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• decreased grip strength_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0010053129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol
• abnormal miniature excitatory postsynaptic currents_Mapk8ip2<tm1.1Gol>/Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/0004753129SSvEvMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11GolMapk8ip2tm11Gol

class

http://purl.org/net/cito/citesAsAuthority

• Mapk8ip2<tm1Gol>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867720
• Mapk8ip2<tm1.1Gol>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867721

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12265
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12265