Shuling. Zhang, et.al., Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production., Blood, 2011, 117

http://rdf.ncbi.nlm.nih.gov/pubmed/21079150

Shuling. Zhang, et.al., Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production., Blood, 2011, 117

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mtor<tm1Lgm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889219
• Mtor<tm1.1Lgm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889218

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small spleen_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0000692I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased B cell proliferation_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0005093I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• increased CD4-positive, alpha beta T cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0008074I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• increased CD8-positive, alpha-beta T cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0008078I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased monocyte cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0000223I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased B cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0005017I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased IgG level_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0001805I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• abnormal T cell morphology_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0008037I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased follicular B cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0008174I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased transitional stage T1 B cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0009923I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• preweaning lethality, incomplete penetrance_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0011110I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• abnormal B cell physiology_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0002459I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• abnormal humoral immune response_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0001800I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• abnormal T cell physiology_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0002444I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased neutrophil cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0000222I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased IgM level_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0001806I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased splenocyte apoptosis_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0009341I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased plasma cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0008098I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• abnormal B cell differentiation_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0002144I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased thymocyte number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0000715I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased body weight_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0001262I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased splenocyte proliferation_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0009335I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased body size_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0001265I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased double-positive T cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0005092I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm
• decreased marginal zone B cell number_Mtor<tm1Lgm>/Mtor<tm1Lgm>
  http://metadb.riken.jp/0008182I129S1SvC57BL6Mtortm1LgmMtortm1LgmMtortm1Lgm

class

http://purl.org/net/cito/citesAsAuthority

• Mtor<tm1Lgm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889219
• Mtor<tm1.1Lgm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889218