Gwen V. Childs, et.al., The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity., Endocrinology, 2011, 152

http://rdf.ncbi.nlm.nih.gov/pubmed/21084451

Gwen V. Childs, et.al., The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity., Endocrinology, 2011, 152

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethality, incomplete penetrance_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0010831I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua
• increased lean body mass_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0003960I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua
• decreased somatotroph cell number_Lepr<tm1.1Chua>/Lepr<+>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0008329I129C57BL6FVBLeprtm11ChuaLeprTgGh1crebKnmn0Leprtm11ChuaTgGh1crebKnmnLepr
• decreased somatotroph cell number_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0008329I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua
• decreased circulating growth hormone level_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0005120I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua
• obese_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0001261I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua
• increased total body fat amount_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0010024I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua
• increased circulating leptin level_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0005669I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua
• increased body weight_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Gh1-cre)bKnmn/0
  http://metadb.riken.jp/0001260I129C57BL6FVBLeprtm11ChuaLeprtm11ChuaTgGh1crebKnmn0TgGh1crebKnmnLeprtm11Chua