Brice. Ongali, et.al., Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease., The American journal of pathology, 2010, 177

http://rdf.ncbi.nlm.nih.gov/pubmed/21088218

Brice. Ongali, et.al., Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease., The American journal of pathology, 2010, 177

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• astrocytosis_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003354IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• abnormal brain vasculature morphology_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0004950IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• abnormal somatosensory cortex physiology_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0001908IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• cerebral amyloid angiopathy_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0004254IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• abnormal spatial learning_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0001463IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• abnormal blood vessel morphology_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0001614IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• abnormal spatial reference memory_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0008414IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• amyloid beta deposits_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003329IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• abnormal brain pia mater morphology_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0009026IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• decreased vasodilation_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0005591IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms
• abnormal cholinergic neuron morphology_Tg(Gfap-TGFB1)64Lms/0,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0001038IBALBcC57BL6DBA2SJLTgGfapTGFB164Lms0TgPDGFBAPPSwInd20Lms0TgGfapTGFB164LmsTgPDGFBAPPSwInd20Lms