Xue. Gao, et.al., The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice., PloS one, 2010, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/21103374

Xue. Gao, et.al., The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice., PloS one, 2010, 5

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fto<tm1.3Pzg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4868745
• Fto<tm1.1Pzg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4868738
• Fto<tm1.2Pzg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4868744

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal carbon dioxide production_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0008962I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• abnormal oxygen consumption_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0005288I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• increased total body fat amount_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0010024I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• abnormal eating behavior_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0001431I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• abnormal eating behavior_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0001431I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• postnatal lethality, incomplete penetrance_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0011086I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• cachexia_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0005150I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• decreased circulating insulin-like growth factor I level_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0004701I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• decreased body length_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0001258I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• decreased circulating insulin-like growth factor I level_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0004701I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• abnormal oxygen consumption_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005288I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• postnatal growth retardation_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001732I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• abnormal carbon dioxide production_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008962I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• decreased lean body mass_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0003961I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• decreased bone mineral density_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000063I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• postnatal lethality, incomplete penetrance_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0011086I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• decreased lean body mass_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0003961I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• decreased circulating insulin-like growth factor I level_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004701I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• increased total body fat amount_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0010024I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• abnormal oxygen consumption_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0005288I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• decreased lean body mass_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003961I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• dermatitis_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0001194I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• decreased body weight_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• dermatitis_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0001194I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• decreased body weight_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• decreased body length_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0001258I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• cachexia_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0005150I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• postnatal growth retardation_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0001732I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• abnormal carbon dioxide production_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0008962I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• postnatal growth retardation_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0001732I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• increased susceptibility to diet-induced obesity_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0005658I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• decreased bone mineral density_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0000063I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg
• decreased bone mineral density_Fto<tm1.2Pzg>/Fto<tm1.2Pzg>
  http://metadb.riken.jp/0000063I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm12PzgFtotm12PzgFtotm12Pzg
• abnormal eating behavior_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001431I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• decreased body length_Fto<tm1.1Pzg>/Fto<tm1.1Pzg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001258I129P2OlaHsd129S4SvJaeSorC57BL6SJLFtotm11PzgFtotm11PzgTgNescre1Kln0Ftotm11PzgTgNescre1Kln
• increased susceptibility to diet-induced obesity_Fto<tm1.3Pzg>/Fto<tm1.3Pzg>
  http://metadb.riken.jp/0005658I129P2OlaHsd129S4SvJaeSorC57BL6Ftotm13PzgFtotm13PzgFtotm13Pzg

class

http://purl.org/net/cito/citesAsAuthority

• Fto<tm1.3Pzg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4868745
• Fto<tm1.1Pzg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4868738
• Fto<tm1.2Pzg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4868744

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD00783
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00783
• CD20478
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20478