Zhen. Liu, et.al., Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models., Human molecular genetics, 2011, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/21131289

Zhen. Liu, et.al., Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models., Human molecular genetics, 2011, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Wnk1<tm2Cihu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5440881

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased systemic arterial systolic blood pressure_Tg(Cdh16-Wnk1*)#Cihu/0
  http://metadb.riken.jp/0006264IC57BL6TgCdh16Wnk1Cihu0TgCdh16Wnk1Cihu
• increased circulating sodium level_Wnk1<tm2Cihu>/Wnk1<tm2Cihu>
  http://metadb.riken.jp/0005633129Wnk1tm2CihuWnk1tm2CihuWnk1tm2CihuWnk1tm2Cihu
• decreased systemic arterial diastolic blood pressure_Tg(Cdh16-Wnk1*)#Cihu/0
  http://metadb.riken.jp/0006263IC57BL6TgCdh16Wnk1Cihu0TgCdh16Wnk1Cihu
• increased circulating aldosterone level_Tg(Cdh16-Wnk1*)#Cihu/0
  http://metadb.riken.jp/0002666IC57BL6TgCdh16Wnk1Cihu0TgCdh16Wnk1Cihu
• increased circulating angiotensinogen level_Tg(Cdh16-Wnk1*)#Cihu/0
  http://metadb.riken.jp/0006375IC57BL6TgCdh16Wnk1Cihu0TgCdh16Wnk1Cihu
• decreased urine sodium level_Wnk1<tm2Cihu>/Wnk1<tm2Cihu>
  http://metadb.riken.jp/0006317129Wnk1tm2CihuWnk1tm2CihuWnk1tm2CihuWnk1tm2Cihu
• decreased circulating potassium level_Tg(Cdh16-Wnk1*)#Cihu/0
  http://metadb.riken.jp/0005628IC57BL6TgCdh16Wnk1Cihu0TgCdh16Wnk1Cihu
• increased systemic arterial systolic blood pressure_Wnk1<tm2Cihu>/Wnk1<tm2Cihu>
  http://metadb.riken.jp/0006144129Wnk1tm2CihuWnk1tm2CihuWnk1tm2CihuWnk1tm2Cihu
• increased urine potassium level_Tg(Cdh16-Wnk1*)#Cihu/0
  http://metadb.riken.jp/0005619IC57BL6TgCdh16Wnk1Cihu0TgCdh16Wnk1Cihu
• increased urine sodium level_Tg(Cdh16-Wnk1*)#Cihu/0
  http://metadb.riken.jp/0006316IC57BL6TgCdh16Wnk1Cihu0TgCdh16Wnk1Cihu

class

http://purl.org/net/cito/citesAsAuthority

• Wnk1<tm2Cihu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5440881

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD27615
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD27615