Christopher. Li, et.al., Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/21135236

Christopher. Li, et.al., Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgE level_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0002497NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• abnormal epidermal layer morphology_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001216NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• dry skin_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0003853NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• impaired skin barrier function_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0002796NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• abnormal T cell physiology_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0002444NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• epidermal hyperplasia_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001222NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• dermatitis_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001194NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• premature death_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0002083NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• abnormal skin morphology_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0002060NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• increased IgG1 level_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0008499NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• skin edema_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001786NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• abnormal keratinocyte morphology_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0002655NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• abnormal blood vessel morphology_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001614NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• thick epidermis_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001219NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• postnatal lethality, incomplete penetrance_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0011086NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• increased mast cell number_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0000324NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• scaly skin_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001192NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• epidermal spongiosis_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0009795NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu
• acanthosis_Casp8<tm1Hed>/Casp8<tm1Hed>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001874NSCasp8tm1HedCasp8tm1HedTgKRT14cre1Efu0Casp8tm1HedTgKRT14cre1Efu

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03127
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03127
• CD10841
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10841