Stephanie C. Colvin, et.al., Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21149718

Stephanie C. Colvin, et.al., Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941330

class

http://purl.org/net/cito/citesAsAuthority

• Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941330

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• reduced male fertility_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001922I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal pituitary gland morphology_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0000633I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal craniofacial morphology_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0000428I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• female infertility_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001926I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased prolactin level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005138I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal internal male genitalia morphology_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0009205I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased circulating insulin-like growth factor I level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0004701I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased uterus weight_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0004905I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal spermatogenesis_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001156I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal sex gland secretion_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0002779I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• delayed sexual maturation_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001938I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal thyroid follicle morphology_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0004696I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased adrenocorticotropin level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005128I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• premature death_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0002083I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased activity of thyroid_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0003503I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased lactotroph cell number_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0008332I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• adenohypophysis hypoplasia_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0008365I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• small seminal vesicle_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001157I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased body size_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001265I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal uterus development_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0003572I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased gonadotroph cell number_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0008335I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• small uterus_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0002637I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• postnatal growth retardation_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001732I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• perinatal lethality, incomplete penetrance_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0011090I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased circulating prolactin level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005121I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• cachexia_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005150I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal pituitary hormone level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0003965I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased circulating thyroxine level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005478I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• small prostate gland_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0002774I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased luteinizing hormone level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005132I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal fertility/fecundity_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0002161I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• abnormal uterus morphology_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001120I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased follicle stimulating hormone level_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005130I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• decreased survivor rate_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0008770I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• azoospermia_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0005159I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr
• small testis_Lhx3<tm1.1Sjr>/Lhx3<tm1.1Sjr>
  http://metadb.riken.jp/0001147I129SSvEvC57BL6JFVBNLhx3tm11SjrLhx3tm11SjrLhx3tm11Sjr

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD20991
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20991