Stefan. Herrmann, et.al., Insights into sick sinus syndrome from an inducible mouse model., Cardiovascular research, 2011, 90

http://rdf.ncbi.nlm.nih.gov/pubmed/21193513

Stefan. Herrmann, et.al., Insights into sick sinus syndrome from an inducible mouse model., Cardiovascular research, 2011, 90

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• irregular heartbeat_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0001636I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4
• premature death_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0002083I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4
• cardiac fibrosis_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0003141I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4
• prolonged PR interval_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0003896I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4
• increased heart rate variability_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0003928I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4
• abnormal sinoatrial node morphology_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0004115I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4
他2件を見る
• decreased heart rate_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0005333I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4
• atrioventricular block_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Hcn4<tm1(cre/ERT2)Anlu>/Hcn4<+>
  http://metadb.riken.jp/0010519I129SSvEvGtROSA26Sortm1DTAJpmbGtROSA26SorHcn4tm1creERT2AnluHcn4GtROSA26SorGtROSA26Sortm1DTAJpmbHcn4tm1creERT2AnluHcn4