Daniel. Kopinke, et.al., Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas., Development (Cambridge, England), 2011, 138

http://rdf.ncbi.nlm.nih.gov/pubmed/21205788

Daniel. Kopinke, et.al., Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas., Development (Cambridge, England), 2011, 138

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased intestinal adenoma incidence_Ctnnb1<tm1Mmt>/Ctnnb1<+>
  http://metadb.riken.jp/0002404I129S1Sv129S4SvJaeSor129X1SvJCtnnb1tm1MmtCtnnb1Ctnnb1Ctnnb1tm1Mmt
• abnormal small intestine morphology_Ctnnb1<tm1Mmt>/Ctnnb1<+>
  http://metadb.riken.jp/0000496I129S1Sv129S4SvJaeSor129X1SvJCtnnb1tm1MmtCtnnb1Ctnnb1Ctnnb1tm1Mmt
• abnormal small intestinal crypt cell proliferation_Ctnnb1<tm1Mmt>/Ctnnb1<+>
  http://metadb.riken.jp/0010157I129S1Sv129S4SvJaeSor129X1SvJCtnnb1tm1MmtCtnnb1Ctnnb1Ctnnb1tm1Mmt
• abnormal pancreas development_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Hes1<tm1(cre/ERT2)Lcm>/Hes1<+>
  http://metadb.riken.jp/0003934I129S1Sv129S4SvJaeSor129X1SvJGtROSA26Sortm1Notch1DamGtROSA26SorHes1tm1creERT2LcmHes1Hes1Hes1tm1creERT2LcmGtROSA26Sortm1Notch1DamGtROSA26Sor
• embryonic lethality during organogenesis, complete penetrance_Hes1<tm1(cre/ERT2)Lcm>/Hes1<tm1(cre/ERT2)Lcm>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJHes1tm1creERT2LcmHes1tm1creERT2LcmHes1tm1creERT2Lcm
• abnormal pancreas development_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003934I129S4SvJaeSorC57BL6CBAGtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam0TgPdx1cre891DamGtROSA26SorGtROSA26Sortm1Notch1Dam
• no abnormal phenotype detected_Hes1<tm1(cre/ERT2)Lcm>/Hes1<+>
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJHes1tm1creERT2LcmHes1Hes1Hes1tm1creERT2Lcm

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD16303
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16303