Mirko. Baruscotti, et.al., Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21220308

Mirko. Baruscotti, et.al., Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hcn4<tm1.1Ggc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4888968

class

http://purl.org/net/cito/citesAsAuthority

• Hcn4<tm1.1Ggc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4888968

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• prolonged PQ interval_Hcn4<tm1.1Ggc>/Hcn4<tm1.1Ggc>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0011953I129SSvEvC57BL6FVBNHcn4tm11GgcHcn4tm11GgcA1cfTgMyh6creEsr11Jmk0Hcn4tm11GgcA1cfTgMyh6creEsr11Jmk
• abnormal impulse conducting system conduction_Hcn4<tm1.1Ggc>/Hcn4<tm1.1Ggc>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003137I129SSvEvC57BL6FVBNHcn4tm11GgcHcn4tm11GgcA1cfTgMyh6creEsr11Jmk0Hcn4tm11GgcA1cfTgMyh6creEsr11Jmk
• decreased heart rate_Hcn4<tm1.1Ggc>/Hcn4<tm1.1Ggc>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005333I129SSvEvC57BL6FVBNHcn4tm11GgcHcn4tm11GgcA1cfTgMyh6creEsr11Jmk0Hcn4tm11GgcA1cfTgMyh6creEsr11Jmk
• premature death_Hcn4<tm1.1Ggc>/Hcn4<tm1.1Ggc>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002083I129SSvEvC57BL6FVBNHcn4tm11GgcHcn4tm11GgcA1cfTgMyh6creEsr11Jmk0Hcn4tm11GgcA1cfTgMyh6creEsr11Jmk
• atrioventricular block_Hcn4<tm1.1Ggc>/Hcn4<tm1.1Ggc>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0010519I129SSvEvC57BL6FVBNHcn4tm11GgcHcn4tm11GgcA1cfTgMyh6creEsr11Jmk0Hcn4tm11GgcA1cfTgMyh6creEsr11Jmk
• abnormal sinoatrial node conduction_Hcn4<tm1.1Ggc>/Hcn4<tm1.1Ggc>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0006142I129SSvEvC57BL6FVBNHcn4tm11GgcHcn4tm11GgcA1cfTgMyh6creEsr11Jmk0Hcn4tm11GgcA1cfTgMyh6creEsr11Jmk