Sanae. Sakami, et.al., Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations., The Journal of biological chemistry, 2011, 286

http://rdf.ncbi.nlm.nih.gov/pubmed/21224384

Sanae. Sakami, et.al., Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations., The Journal of biological chemistry, 2011, 286

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rho<tm1.1Kpal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4947230

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thin retinal outer nuclear layer_Rho<tm1.1Kpal>/Rho<tm1.1Kpal>
  http://metadb.riken.jp/0008515I129S6SvEvTacC57BL6FVBNRhotm11KpalRhotm11KpalRhotm11Kpal
• retinal rod cell degeneration_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0008451I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal
• abnormal retinal layer morphology_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0003727I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal
• retinal rod cell degeneration_Lrat<tm1Kpal>/Lrat<tm1Kpal>,Rho<tm1.1Kpal>/Rho<+>,Rpe65<450L>/Rpe65<450M>
  http://metadb.riken.jp/0008451I129S6SvEvTacC57BL6FVBNLrattm1KpalLrattm1KpalRhotm11KpalRhoRpe65450LRpe65450MRhoRpe65450MRpe65450LRhotm11KpalLrattm1Kpal
• decreased retinal photoreceptor cell number_Lrat<tm1Kpal>/Lrat<tm1Kpal>,Rho<tm1.1Kpal>/Rho<+>,Rpe65<450L>/Rpe65<450M>
  http://metadb.riken.jp/0001327I129S6SvEvTacC57BL6FVBNLrattm1KpalLrattm1KpalRhotm11KpalRhoRpe65450LRpe65450MRhoRpe65450MRpe65450LRhotm11KpalLrattm1Kpal
• thin retinal outer nuclear layer_Lrat<tm1Kpal>/Lrat<tm1Kpal>,Rho<tm1.1Kpal>/Rho<+>,Rpe65<450L>/Rpe65<450M>
  http://metadb.riken.jp/0008515I129S6SvEvTacC57BL6FVBNLrattm1KpalLrattm1KpalRhotm11KpalRhoRpe65450LRpe65450MRhoRpe65450MRpe65450LRhotm11KpalLrattm1Kpal
• disorganized photoreceptor outer segment_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0008586I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal
• thin retinal outer nuclear layer_Lrat<tm1Kpal>/Lrat<tm1Kpal>
  http://metadb.riken.jp/0008515I129S6SvEvTacLrattm1KpalLrattm1KpalLrattm1Kpal
• thin retinal outer nuclear layer_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0008515I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal
• abnormal rod electrophysiology_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0004021I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal
• decreased retinal rod cell number_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0008453I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal
• retinal degeneration_Lrat<tm1Kpal>/Lrat<tm1Kpal>,Rho<tm1.1Kpal>/Rho<+>,Rpe65<450L>/Rpe65<450M>
  http://metadb.riken.jp/0001326I129S6SvEvTacC57BL6FVBNLrattm1KpalLrattm1KpalRhotm11KpalRhoRpe65450LRpe65450MRhoRpe65450MRpe65450LRhotm11KpalLrattm1Kpal
• decreased retinal photoreceptor cell number_Rho<tm1.1Kpal>/Rho<tm1.1Kpal>
  http://metadb.riken.jp/0001327I129S6SvEvTacC57BL6FVBNRhotm11KpalRhotm11KpalRhotm11Kpal
• abnormal cone electrophysiology_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0004022I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal
• abnormal retinal rod cell outer segment morphology_Lrat<tm1Kpal>/Lrat<tm1Kpal>,Rho<tm1.1Kpal>/Rho<+>,Rpe65<450L>/Rpe65<450M>
  http://metadb.riken.jp/0008456I129S6SvEvTacC57BL6FVBNLrattm1KpalLrattm1KpalRhotm11KpalRhoRpe65450LRpe65450MRhoRpe65450MRpe65450LRhotm11KpalLrattm1Kpal
• retinal photoreceptor degeneration_Lrat<tm1Kpal>/Lrat<tm1Kpal>,Rho<tm1.1Kpal>/Rho<+>,Rpe65<450L>/Rpe65<450M>
  http://metadb.riken.jp/0008450I129S6SvEvTacC57BL6FVBNLrattm1KpalLrattm1KpalRhotm11KpalRhoRpe65450LRpe65450MRhoRpe65450MRpe65450LRhotm11KpalLrattm1Kpal
• abnormal retinal rod cell outer segment morphology_Rho<tm1.1Kpal>/Rho<+>
  http://metadb.riken.jp/0008456I129S6SvEvTacC57BL6FVBNRhotm11KpalRhoRhoRhotm11Kpal

class

http://purl.org/net/cito/citesAsAuthority

• Rho<tm1.1Kpal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4947230