Nicolas. Fossat, et.al., Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo., Development (Cambridge, England), 2011, 138

http://rdf.ncbi.nlm.nih.gov/pubmed/21228006

Nicolas. Fossat, et.al., Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo., Development (Cambridge, England), 2011, 138

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal head size_Ctnnb1<Bfc>/Ctnnb1<Bfc>,Dkk1<tm1Lmgd>/Dkk1<+>
  http://metadb.riken.jp/0011496EI129SvBALBcCrlC3HHeNCrlorI129SvBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1BfcDkk1tm1LmgdDkk1Ctnnb1BfcDkk1Dkk1tm1Lmgd
• forebrain hypoplasia_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0000784EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1
• anophthalmia_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0001293EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1
• kinked tail_Lrp6<Gw>/Lrp6<Gw>
  http://metadb.riken.jp/0000585I101HBALBcC3HHeHLrp6GwLrp6GwLrp6Gw
• abnormal forebrain morphology_Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0000783I101HBALBcC3HHeHLrp6GwLrp6Lrp6Lrp6Gw
• abnormal head morphology_Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0000432I101HBALBcC3HHeHLrp6GwLrp6Lrp6Lrp6Gw
• abnormal eye morphology_Ctnnb1<Bfc>/Ctnnb1<+>,Dkk1<tm1Lmgd>/Dkk1<+>
  http://metadb.riken.jp/0002092EI129SvBALBcCrlC3HHeNCrlorI129SvBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Dkk1tm1LmgdDkk1Dkk1tm1LmgdCtnnb1Dkk1Ctnnb1Bfc
• abnormal telencephalon morphology_Lrp6<Gw>/Lrp6<Gw>
  http://metadb.riken.jp/0000787I101HBALBcC3HHeHLrp6GwLrp6GwLrp6Gw
• kinked tail_Lrp6<Gw>/Lrp6<+>,Wnt3<tm1Brd>/Wnt3<+>
  http://metadb.riken.jp/0000585I101H129S7SvEvBrdBALBcC3HLrp6GwLrp6Wnt3tm1BrdWnt3Wnt3tm1BrdLrp6Wnt3Lrp6Gw
• preweaning lethality, incomplete penetrance_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0011110EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1
• forebrain hypoplasia_Lrp6<Gw>/Lrp6<Gw>
  http://metadb.riken.jp/0000784I101HBALBcC3HHeHLrp6GwLrp6GwLrp6Gw
• abnormal head morphology_Dkk1<tm1Lmgd>/Dkk1<+>,Lrp6<Gw>/Lrp6<Gw>
  http://metadb.riken.jp/0000432I101H129SvBALBcC3HDkk1tm1LmgdDkk1Lrp6GwLrp6GwDkk1tm1LmgdDkk1Lrp6Gw
• abnormal head morphology_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0000432EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1
• abnormal head size_Ctnnb1<Bfc>/Ctnnb1<+>,Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0011496EI101HBALBcCrlC3HorI101HBALBcCrlC3HC57BL6Ctnnb1BfcCtnnb1Lrp6GwLrp6Ctnnb1Lrp6GwCtnnb1BfcLrp6
• abnormal head size_Ctnnb1<Bfc>/Ctnnb1<+>,Dkk1<tm1Lmgd>/Dkk1<+>,Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0011496EI101H129SvBALBcCrlC3HorI101H129SvBALBcCrlC3HC57BL6Ctnnb1BfcCtnnb1Dkk1tm1LmgdDkk1Lrp6GwLrp6Lrp6Lrp6GwCtnnb1BfcDkk1tm1LmgdDkk1Ctnnb1
• abnormal head morphology_Ctnnb1<Bfc>/Ctnnb1<+>,Dkk1<tm1Lmgd>/Dkk1<+>
  http://metadb.riken.jp/0000432EI129SvBALBcCrlC3HHeNCrlorI129SvBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Dkk1tm1LmgdDkk1Dkk1tm1LmgdCtnnb1Dkk1Ctnnb1Bfc
• preweaning lethality, incomplete penetrance_Ctnnb1<Bfc>/Ctnnb1<+>,Dkk1<tm1Lmgd>/Dkk1<+>
  http://metadb.riken.jp/0011110EI129SvBALBcCrlC3HHeNCrlorI129SvBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Dkk1tm1LmgdDkk1Dkk1tm1LmgdCtnnb1Dkk1Ctnnb1Bfc
• preweaning lethality, complete penetrance_Ctnnb1<Bfc>/Ctnnb1<Bfc>
  http://metadb.riken.jp/0011100EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1BfcCtnnb1Bfc
• kinked tail_Dkk1<tm1Lmgd>/Dkk1<+>,Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0000585I101H129SvBALBcC3HDkk1tm1LmgdDkk1Lrp6GwLrp6Lrp6GwDkk1tm1LmgdDkk1Lrp6
• abnormal head morphology_Dkk1<tm1Lmgd>/Dkk1<+>
  http://metadb.riken.jp/0000432I129S1Sv129X1SvJDkk1tm1LmgdDkk1Dkk1Dkk1tm1Lmgd
• cataract_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0001304EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1
• abnormal eye morphology_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0002092EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1
• abnormal head size_Ctnnb1<Bfc>/Ctnnb1<Bfc>
  http://metadb.riken.jp/0011496EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1BfcCtnnb1Bfc
• caudal body truncation_Ctnnb1<Bfc>/Ctnnb1<+>,Dkk1<tm1Lmgd>/Dkk1<+>,Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0004073EI101H129SvBALBcCrlC3HorI101H129SvBALBcCrlC3HC57BL6Ctnnb1BfcCtnnb1Dkk1tm1LmgdDkk1Lrp6GwLrp6Lrp6Lrp6GwCtnnb1BfcDkk1tm1LmgdDkk1Ctnnb1
• microphthalmia_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0001297EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1
• abnormal head morphology_Lrp6<Gw>/Lrp6<Gw>
  http://metadb.riken.jp/0000432I101HBALBcC3HHeHLrp6GwLrp6GwLrp6Gw
• rostral body truncation_Dkk1<tm1Lmgd>/Dkk1<tm1Lmgd>
  http://metadb.riken.jp/0012157I129S1Sv129X1SvJDkk1tm1LmgdDkk1tm1LmgdDkk1tm1Lmgd
• kinked tail_Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0000585I101HBALBcC3HHeHLrp6GwLrp6Lrp6Lrp6Gw
• abnormal head morphology_Dkk1<tm1Lmgd>/Dkk1<+>,Lrp6<Gw>/Lrp6<+>
  http://metadb.riken.jp/0000432I101H129SvBALBcC3HDkk1tm1LmgdDkk1Lrp6GwLrp6Lrp6GwDkk1tm1LmgdDkk1Lrp6
• flattened snout_Ctnnb1<Bfc>/Ctnnb1<+>
  http://metadb.riken.jp/0000447EIBALBcCrlC3HHeNCrlorIBALBcCrlC3HHeNCrlC57BL6Ctnnb1BfcCtnnb1Ctnnb1BfcCtnnb1