Hua V. Lin, et.al., Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues., Diabetes, 2011, 60

http://rdf.ncbi.nlm.nih.gov/pubmed/21266328

Hua V. Lin, et.al., Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues., Diabetes, 2011, 60

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Slc2a4-cre)546Dac
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941207

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pancreatic beta cell morphology_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0005217I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• insulin resistance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0005331I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• abnormal brown adipose tissue morphology_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0002971I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• abnormal pancreatic islet morphology_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0005215I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• abnormal circadian feeding behavior_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0011943I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• hepatic steatosis_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0002628I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• decreased liver glycogen level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0010398I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• abnormal lean body mass_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0003959I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• increased oxygen consumption_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0005289I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• increased brown fat cell lipid droplet size_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0009124I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• decreased pancreatic beta cell number_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0003339I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• abnormal epididymal fat pad morphology_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0006319I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• impaired glucose tolerance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0005293I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• hyperglycemia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0001559I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• increased circulating insulin level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0002079I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• decreased body weight_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0001262I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• increased circulating free fatty acid level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0001554I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• increased circulating glucose level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0005559I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• postnatal growth retardation_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0001732I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn
• abnormal glucose homeostasis_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Slc2a4-cre)546Dac/0
  http://metadb.riken.jp/0002078I129S4SvJaeSorC57BL6FVBInsrtm1KhnInsrtm1KhnTgSlc2a4cre546Dac0TgSlc2a4cre546DacInsrtm1Khn

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Slc2a4-cre)546Dac
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941207

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD28050
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28050