Guorui. Huang, et.al., α3(V) collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues., The Journal of clinical investigation, 2011, 121

http://rdf.ncbi.nlm.nih.gov/pubmed/21293061

Guorui. Huang, et.al., α3(V) collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues., The Journal of clinical investigation, 2011, 121

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col5a3<tm1Dgr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5000519

class

http://purl.org/net/cito/citesAsAuthority

• Col5a3<tm1Dgr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5000519

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased muscle cell glucose uptake_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0030022I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• impaired glucose tolerance_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased pancreas weight_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0009109I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased subcutaneous adipose tissue amount_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0008844I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• abnormal pancreas physiology_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0002693I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased adipocyte glucose uptake_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0030017I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased insulin secretion_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0003059I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• weight loss_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0001263I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• increased pancreatic beta cell apoptosis_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0014117I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• increased physiological sensitivity to xenobiotic_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0008873I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased susceptibility to diet-induced obesity_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0005659I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• hyperglycemia_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0001559I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased circulating insulin level_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0002727I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• insulin resistance_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0005331I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased body weight_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• increased pancreatic islet cell apoptosis_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0014121I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased pancreatic beta cell number_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0003339I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• decreased pancreatic beta cell mass_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0009114I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr
• abnormal glucose homeostasis_Col5a3<tm1Dgr>/Col5a3<tm1Dgr>
  http://metadb.riken.jp/0002078I129S1Sv129X1SvJICRCol5a3tm1DgrCol5a3tm1DgrCol5a3tm1Dgr