Yu. Lei, et.al., Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development., The Journal of experimental medicine, 2011, 208

http://rdf.ncbi.nlm.nih.gov/pubmed/21300913

Yu. Lei, et.al., Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development., The Journal of experimental medicine, 2011, 208

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Aire<tm1.1(cre)Ghr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5296650
• Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5296620

class

http://purl.org/net/cito/citesAsAuthority

• Aire<tm1.1(cre)Ghr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5296650
• Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5296620

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased inflammatory response_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0001846EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• decreased dendritic cell number_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0008127EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• decreased regulatory T cell number_Aire<tm1.1(cre)Ghr>/Aire<tm1.1(cre)Ghr>
  http://metadb.riken.jp/0004974NSAiretm11creGhrAiretm11creGhrAiretm11creGhr
• salivary gland inflammation_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0001870EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• abnormal immune system morphology_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0000685EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• autoimmune response_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0001844EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• decreased dendritic cell number_Aire<tm1.1(cre)Ghr>/Aire<tm1.1(cre)Ghr>
  http://metadb.riken.jp/0008127NSAiretm11creGhrAiretm11creGhrAiretm11creGhr
• increased dendritic cell number_Aire<tm1.1(cre)Ghr>/Aire<tm1.1(cre)Ghr>
  http://metadb.riken.jp/0008126NSAiretm11creGhrAiretm11creGhrAiretm11creGhr
• decreased regulatory T cell number_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0004974EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• heart inflammation_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0001853EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• increased dendritic cell number_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0008126EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• stomach inflammation_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0001873EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• liver inflammation_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0001860EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax
• lacrimal gland inflammation_Xcl1<tm1.1Dnax>/Xcl1<tm1.1Dnax>
  http://metadb.riken.jp/0008880EI129SvBALBcorI129SvC57BL6Xcl1tm11DnaxXcl1tm11DnaxXcl1tm11Dnax