Ana. Nunes, et.al., Loss of amyloid precursor protein in a mouse model of Niemann-Pick type C disease exacerbates its phenotype and disrupts tau homeostasis., Neurobiology of disease, 2011, 42

http://rdf.ncbi.nlm.nih.gov/pubmed/21303697

Ana. Nunes, et.al., Loss of amyloid precursor protein in a mouse model of Niemann-Pick type C disease exacerbates its phenotype and disrupts tau homeostasis., Neurobiology of disease, 2011, 42

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased brain size_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0000774BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N
• decreased brain size_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0000774CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• demyelination_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0000921CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• weight loss_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0001263CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• Purkinje cell degeneration_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0000876CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• impaired coordination_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0001405BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N
• Purkinje cell degeneration_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0000876BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N
• weight loss_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0001263BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N
• increased brain cholesterol level_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0010162CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• astrocytosis_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0003354BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N
• premature death_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0002083BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N
• demyelination_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0000921BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N
• impaired coordination_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0001405CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• premature death_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0002083CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• astrocytosis_App<tm1Dbo>/App<tm1Dbo>,Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0003354CCgApptm1DboNpc1m1NApptm1DboApptm1DboNpc1m1NNpc1m1NApptm1DboNpc1m1N
• increased brain cholesterol level_Npc1<m1N>/Npc1<m1N>
  http://metadb.riken.jp/0010162BALBcNpc1m1NNpc1m1NNpc1m1NNpc1m1N