Sayuri. Takahashi, et.al., Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21383160

Sayuri. Takahashi, et.al., Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ar<tm3.1(AR)Ska>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4946660

class

http://purl.org/net/cito/citesAsAuthority

• Ar<tm3.1(AR)Ska>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4946660

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal tumor morphology_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
  http://metadb.riken.jp/0003448IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgTRAMP8247Ng0TgTRAMP8247NgTgKLKB1creERT21PcnArtm31ARSka
• reduced fertility_Ar<tm3.1(AR)Ska>/Y
  http://metadb.riken.jp/0001921IC57BL6C57BL6JCBAArtm31ARSkaYArtm31ARSka
• increased prostate gland weight_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
  http://metadb.riken.jp/0004961IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgKLKB1creERT21PcnArtm31ARSka
• increased tumor growth/size_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
  http://metadb.riken.jp/0003721IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgTRAMP8247Ng0TgTRAMP8247NgTgKLKB1creERT21PcnArtm31ARSka
• increased circulating testosterone level_Ar<tm3.1(AR)Ska>/Y
  http://metadb.riken.jp/0002781IC57BL6C57BL6JCBAArtm31ARSkaYArtm31ARSka
• small seminiferous tubules_Ar<tm3.1(AR)Ska>/Y
  http://metadb.riken.jp/0001153IC57BL6C57BL6JCBAArtm31ARSkaYArtm31ARSka
• small prostate gland_Ar<tm3.1(AR)Ska>/Y
  http://metadb.riken.jp/0002774IC57BL6C57BL6JCBAArtm31ARSkaYArtm31ARSka
• decreased prostate gland weight_Ar<tm3.1(AR)Ska>/Y
  http://metadb.riken.jp/0004962IC57BL6C57BL6JCBAArtm31ARSkaYArtm31ARSka
• increased prostate gland tumor incidence_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
  http://metadb.riken.jp/0010357IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgTRAMP8247Ng0TgTRAMP8247NgTgKLKB1creERT21PcnArtm31ARSka
• reduced fertility_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
  http://metadb.riken.jp/0001921IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgKLKB1creERT21PcnArtm31ARSka
• abnormal prostate gland physiology_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
  http://metadb.riken.jp/0003607IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgKLKB1creERT21PcnArtm31ARSka
• decreased tumor latency_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
  http://metadb.riken.jp/0010308IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgTRAMP8247Ng0TgTRAMP8247NgTgKLKB1creERT21PcnArtm31ARSka
• increased circulating testosterone level_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
  http://metadb.riken.jp/0002781IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgKLKB1creERT21PcnArtm31ARSka
• premature death_Ar<tm3.1(AR)Ska>/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
  http://metadb.riken.jp/0002083IC57BL6C57BL6JCBAArtm31ARSkaYTgKLKB1creERT21Pcn0TgTRAMP8247Ng0TgTRAMP8247NgTgKLKB1creERT21PcnArtm31ARSka