Claudio J. Villanueva, et.al., TLE3 is a dual-function transcriptional coregulator of adipogenesis., Cell metabolism, 2011, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/21459326

Claudio J. Villanueva, et.al., TLE3 is a dual-function transcriptional coregulator of adipogenesis., Cell metabolism, 2011, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Fabp4-TLE3)#aPton
  http://metadb.riken.jp/db/mgi_rdf/MGI:5007704

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Fabp4-TLE3)#aPton
  http://metadb.riken.jp/db/mgi_rdf/MGI:5007704

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hormone level_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0003953IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• abnormal cell differentiation_Tle3<Gt(XP0165)Wtsi>/Tle3<Gt(XP0165)Wtsi>
  http://metadb.riken.jp/0005076I129P2OlaHsdTle3GtXP0165WtsiTle3GtXP0165WtsiTle3GtXP0165Wtsi
• decreased circulating insulin level_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0002727IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• embryonic lethality, complete penetrance_Tle3<Gt(XP0165)Wtsi>/Tle3<Gt(XP0165)Wtsi>
  http://metadb.riken.jp/0011092I129P2OlaHsdTle3GtXP0165WtsiTle3GtXP0165WtsiTle3GtXP0165Wtsi
• increased insulin sensitivity_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0002891IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• abnormal glucose homeostasis_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0002078IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• decreased energy expenditure_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0004890IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• decreased food intake_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0011940IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• increased epididymal fat pad weight_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0009288IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• abnormal adipose tissue development_Tle3<Gt(XP0165)Wtsi>/Tle3<Gt(XP0165)Wtsi>
  http://metadb.riken.jp/0011167I129P2OlaHsdTle3GtXP0165WtsiTle3GtXP0165WtsiTle3GtXP0165Wtsi
• increased adiponectin level_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0004892IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• improved glucose tolerance_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0005292IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• decreased circulating glucose level_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0005560IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• decreased susceptibility to hepatic steatosis_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0002310IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton
• decreased liver weight_Tg(Fabp4-TLE3)#aPton/0
  http://metadb.riken.jp/0003402IC57BL6TgFabp4TLE3aPton0TgFabp4TLE3aPton