Sankar. Bhattacharyya, et.al., NFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network., The Journal of experimental medicine, 2011, 208

http://rdf.ncbi.nlm.nih.gov/pubmed/21464221

Sankar. Bhattacharyya, et.al., NFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network., The Journal of experimental medicine, 2011, 208

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nfatc1<tm1Rao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5295237
• Tg(Nfatc1-EGFP)#Srf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5295241

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal B cell physiology_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Nfatc2<tm1Rao>/Nfatc2<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0002459IBALBcNfatc1tm1RaoNfatc1tm1RaoNfatc2tm1RaoNfatc2tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethNfatc2tm1RaoCd79a
• abnormal marginal zone B cell physiology_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008193IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• abnormal class switch recombination_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0004816IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• abnormal B cell physiology_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0002459IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• decreased susceptibility to experimental autoimmune encephalomyelitis_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0004800IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• decreased IgG3 level_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0008498IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• decreased B cell proliferation_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0005093IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• decreased IgM level_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0001806IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• increased interleukin-10 secretion_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0008660IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• decreased B cell proliferation_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0005093IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• increased IgM level_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0002494IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• decreased B cell number_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0005017IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• increased B cell apoptosis_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008782IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• decreased B-1a cell number_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008168IBALBcNfatc1tm1RaoNfatc1tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethCd79a
• decreased interleukin-2 secretion_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Nfatc2<tm1Rao>/Nfatc2<tm1Rao>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008688IBALBcNfatc1tm1RaoNfatc1tm1RaoNfatc2tm1RaoNfatc2tm1RaoCd79atm1creRethCd79aNfatc1tm1RaoCd79atm1creRethNfatc2tm1RaoCd79a
• abnormal class switch recombination_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0004816IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• decreased IgG2a level_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0008496IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• abnormal B cell physiology_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0002459IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao
• decreased interleukin-2 secretion_Nfatc1<tm1Rao>/Nfatc1<tm1Rao>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0008688IC57BL6CBANfatc1tm1RaoNfatc1tm1RaoTgFcer2acre5Mbu0TgFcer2acre5MbuNfatc1tm1Rao

class

http://purl.org/net/cito/citesAsAuthority

• Nfatc1<tm1Rao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5295237
• Tg(Nfatc1-EGFP)#Srf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5295241