Tatsuya. Tominaga, et.al., Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy., The Journal of biological chemistry, 2011, 286

http://rdf.ncbi.nlm.nih.gov/pubmed/21471216

Tatsuya. Tominaga, et.al., Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy., The Journal of biological chemistry, 2011, 286

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Actb-GFP,-Bmp4)1Csk
  http://metadb.riken.jp/db/mgi_rdf/MGI:5291512
• Tg(CAG-cre/Esr1*)67Csk
  http://metadb.riken.jp/db/mgi_rdf/MGI:5291515

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Bmp4<tm1Blh>/Bmp4<+>
  http://metadb.riken.jp/0001262I129S2SvPasC57BL6Bmp4tm1BlhBmp4Bmp4Bmp4tm1Blh
• albuminuria_Tg(Actb-GFP,-Bmp4)1Csk/0,Tg(CAG-cre/Esr1*)67Csk/0
  http://metadb.riken.jp/0002871C57BL6TgActbGFPBmp41CskTgCAGcreEsr167CskTgActbGFPBmp41Csk0TgCAGcreEsr167Csk0TgCAGcreEsr167CskTgActbGFPBmp41Csk
• glomerulosclerosis_Tg(Actb-GFP,-Bmp4)1Csk/0,Tg(CAG-cre/Esr1*)67Csk/0
  http://metadb.riken.jp/0005264C57BL6TgActbGFPBmp41CskTgCAGcreEsr167CskTgActbGFPBmp41Csk0TgCAGcreEsr167Csk0TgCAGcreEsr167CskTgActbGFPBmp41Csk
• abnormal renal glomerulus morphology_Tg(Actb-GFP,-Bmp4)1Csk/0,Tg(CAG-cre/Esr1*)67Csk/0
  http://metadb.riken.jp/0005325C57BL6TgActbGFPBmp41CskTgCAGcreEsr167CskTgActbGFPBmp41Csk0TgCAGcreEsr167Csk0TgCAGcreEsr167CskTgActbGFPBmp41Csk
• abnormal renal glomerulus morphology_Bmp4<tm1Blh>/Bmp4<+>
  http://metadb.riken.jp/0005325I129S2SvPasC57BL6Bmp4tm1BlhBmp4Bmp4Bmp4tm1Blh
• increased circulating glucose level_Bmp4<tm1Blh>/Bmp4<+>
  http://metadb.riken.jp/0005559I129S2SvPasC57BL6Bmp4tm1BlhBmp4Bmp4Bmp4tm1Blh

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Actb-GFP,-Bmp4)1Csk
  http://metadb.riken.jp/db/mgi_rdf/MGI:5291512
• Tg(CAG-cre/Esr1*)67Csk
  http://metadb.riken.jp/db/mgi_rdf/MGI:5291515