Roch-Philippe. Charles, et.al., Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse., Cancer research, 2011, 71

http://rdf.ncbi.nlm.nih.gov/pubmed/21512141

Roch-Philippe. Charles, et.al., Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse., Cancer research, 2011, 71

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Tg-cre/ERT2)#Mmcm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5780075

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Tg-cre/ERT2)#Mmcm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5780075

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased birth weight_Braf<tm1Mmcm>/?,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0009674I129P2OlaHsdFVBNCrBraftm1MmcmTgTPOcre1Shk0TgTPOcre1ShkBraftm1Mmcm
• increased circulating thyroid-stimulating hormone level_Braf<tm1Mmcm>/Braf<+>,Tg(Tg-cre/ERT2)#Mmcm/0
  http://metadb.riken.jp/0005122I129P2OlaHsdBraftm1MmcmBrafTgTgcreERT2Mmcm0Braftm1MmcmTgTgcreERT2MmcmBraf
• abnormal thyroid gland morphology_Braf<tm1Mmcm>/Braf<+>,Tg(Tg-cre/ERT2)#Mmcm/0
  http://metadb.riken.jp/0000681I129P2OlaHsdBraftm1MmcmBrafTgTgcreERT2Mmcm0Braftm1MmcmTgTgcreERT2MmcmBraf
• abnormal thyroid follicle morphology_Braf<tm1Mmcm>/Braf<+>,Tg(Tg-cre/ERT2)#Mmcm/0
  http://metadb.riken.jp/0004696I129P2OlaHsdBraftm1MmcmBrafTgTgcreERT2Mmcm0Braftm1MmcmTgTgcreERT2MmcmBraf
• increased thyroid carcinoma incidence_Braf<tm1Mmcm>/Braf<+>,Tg(Tg-cre/ERT2)#Mmcm/0
  http://metadb.riken.jp/0010346I129P2OlaHsdBraftm1MmcmBrafTgTgcreERT2Mmcm0Braftm1MmcmTgTgcreERT2MmcmBraf
• decreased activity of thyroid_Braf<tm1Mmcm>/Braf<+>,Tg(Tg-cre/ERT2)#Mmcm/0
  http://metadb.riken.jp/0003503I129P2OlaHsdBraftm1MmcmBrafTgTgcreERT2Mmcm0Braftm1MmcmTgTgcreERT2MmcmBraf
• decreased circulating thyroxine level_Braf<tm1Mmcm>/Braf<+>,Tg(Tg-cre/ERT2)#Mmcm/0
  http://metadb.riken.jp/0005478I129P2OlaHsdBraftm1MmcmBrafTgTgcreERT2Mmcm0Braftm1MmcmTgTgcreERT2MmcmBraf
• enlarged thyroid gland_Braf<tm1Mmcm>/Braf<+>,Tg(Tg-cre/ERT2)#Mmcm/0
  http://metadb.riken.jp/0005355I129P2OlaHsdBraftm1MmcmBrafTgTgcreERT2Mmcm0Braftm1MmcmTgTgcreERT2MmcmBraf