Mark P. Boldin, et.al., miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice., The Journal of experimental medicine, 2011, 208

http://rdf.ncbi.nlm.nih.gov/pubmed/21555486

Mark P. Boldin, et.al., miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice., The Journal of experimental medicine, 2011, 208

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mir146<tm2.1Bal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5049868

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased hemoglobin content_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0002874I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• myeloid hyperplasia_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0010373I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• abnormal spleen B cell follicle morphology_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008470I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased circulating interleukin-10 level_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008593IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• decreased hematocrit_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0000208I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased circulating tumor necrosis factor level_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008553I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased acute inflammation_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0005088I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased macrophage nitric oxide production_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0011076IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased susceptibility to endotoxin shock_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008735I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased interleukin-6 secretion_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008705IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• premature death_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0002083IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• anemia_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0001577I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased tumor incidence_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0002020I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• abnormal T cell activation_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0001828IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased susceptibility to endotoxin shock_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008735IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased circulating interleukin-6 level_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008596I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• abnormal bone marrow cell physiology_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0009278I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased tumor necrosis factor secretion_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008560IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased circulating interleukin-1 beta level_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008641I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• abnormal macrophage physiology_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0002451I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• myeloid hyperplasia_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0010373IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• abnormal macrophage physiology_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0002451IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• abnormal immune system physiology_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0001790IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• abnormal immune tolerance_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0005000IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• abnormal T cell activation_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0001828I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• enlarged spleen_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0000691I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased spleen germinal center size_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008483I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• abnormal immune tolerance_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0005000I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased interleukin-1 beta secretion_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008657I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• decreased lymphocyte cell number_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0005016I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• enlarged lymph nodes_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0000702I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased circulating interleukin-1 beta level_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008641IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased hemolymphoid system tumor incidence_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0010296I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased circulating tumor necrosis factor level_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008553IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased interleukin-6 secretion_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008705I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• thrombocytopenia_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0003179I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased interleukin-1 beta secretion_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008657IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased follicular lymphoma incidence_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0009317I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased susceptibility to bacterial infection induced morbidity/mortality_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0009788IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• premature death_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0002083I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased tumor necrosis factor secretion_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008560I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased macrophage nitric oxide production_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0011076I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased circulating interleukin-6 level_Mir146<tm1.1Bal>/Mir146<tm1.1Bal>
  http://metadb.riken.jp/0008596IC57BL6FVBNMir146tm11BalMir146tm11BalMir146tm11Bal
• increased spleen germinal center number_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008481I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased spleen weight_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0004952I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased anti-double stranded DNA antibody level_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0004762I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• abnormal immune system physiology_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0001790I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased susceptibility to bacterial infection induced morbidity/mortality_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0009788I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• decreased monocyte cell number_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0000223I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• increased circulating interleukin-10 level_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0008593I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal
• extramedullary hematopoiesis_Mir146<tm2.1Bal>/Mir146<tm2.1Bal>
  http://metadb.riken.jp/0000240I129S1SvC57BL6FVBNMir146tm21BalMir146tm21BalMir146tm21Bal

class

http://purl.org/net/cito/citesAsAuthority

• Mir146<tm2.1Bal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5049868