Haiyan. Chen, et.al., Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development., Cells, tissues, organs, 2011, 194

http://rdf.ncbi.nlm.nih.gov/pubmed/21597273

Haiyan. Chen, et.al., Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development., Cells, tissues, organs, 2011, 194

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Runx2<tm1Javed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5582325

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal craniofacial bone morphology_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0002116IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• absent vertebrae_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000138IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• decreased birth weight_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0009674IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• abnormal long bone epiphyseal plate morphology_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003055IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• short ribs_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0004672IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• respiratory failure_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0001953IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• abnormal metatarsal bone morphology_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003072IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• neonatal lethality, complete penetrance_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0011087IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• decreased birth body size_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0009703IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• absent metacarpal bones_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003074IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• absent scapula_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0004341IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• abnormal pelvic girdle bone morphology_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0004509IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed
• abnormal limb bone morphology_Runx2<tm1Javed>/Runx2<tm1Javed>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0002115IC57BL6SJLRunx2tm1JavedRunx2tm1JavedTgCol2a1cre1Bhr0TgCol2a1cre1BhrRunx2tm1Javed

class

http://purl.org/net/cito/citesAsAuthority

• Runx2<tm1Javed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5582325