Weihua. Song, et.al., Molecular mechanism of the E99K mutation in cardiac actin (ACTC Gene) that causes apical hypertrophy in man and mouse., The Journal of biological chemistry, 2011, 286

http://rdf.ncbi.nlm.nih.gov/pubmed/21622575

Weihua. Song, et.al., Molecular mechanism of the E99K mutation in cardiac actin (ACTC Gene) that causes apical hypertrophy in man and mouse., The Journal of biological chemistry, 2011, 286

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-ACTC1*E99K)#Sbm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5543406

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged heart_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0000274IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• weight loss_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0001263IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• cardiac hypertrophy_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0001625IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• premature death_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0002083IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• disorganized myocardium_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0002190IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• heart left ventricle hypertrophy_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0002625IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
他14件を見る
• dilated cardiomyopathy_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0002795IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• abnormal impulse conducting system conduction_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0003137IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• decreased cardiac output_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0003393IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• increased left ventricle diastolic pressure_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0003819IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• abnormal cardiac muscle relaxation_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0004084IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• abnormal myocardial fiber physiology_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0004215IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• decreased cardiac muscle contractility_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0005140IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• cardiac interstitial fibrosis_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0005608IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• abnormal heart position or orientation_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0006065IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• congestive heart failure_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0006138IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• atrial fibrillation_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0008543IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• enlarged heart atrium_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0008725IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• pleural effusion_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0010334IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm
• decreased cardiac stroke volume_Tg(Myh6-ACTC1*E99K)#Sbm/0
  http://metadb.riken.jp/0011952IC57BL10CBACaTgMyh6ACTC1E99KSbm0TgMyh6ACTC1E99KSbm

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-ACTC1*E99K)#Sbm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5543406