Maryam. Ahmadian, et.al., Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype., Cell metabolism, 2011, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/21641555

Maryam. Ahmadian, et.al., Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype., Cell metabolism, 2011, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pnpla2<tm1.1Hsul>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5296237

class

http://purl.org/net/cito/citesAsAuthority

• Pnpla2<tm1.1Hsul>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5296237

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal oxygen consumption_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005288I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased susceptibility to diet-induced obesity_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005658I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased white fat cell size_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009118I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• impaired adaptive thermogenesis_Ppara<tm1Gonz>/Ppara<tm1Gonz>
  http://metadb.riken.jp/0011049I129S4SvJaePparatm1GonzPparatm1GonzPparatm1Gonz
• increased total fat pad weight_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0008908I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased gonadal fat pad weight_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009285I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased insulin sensitivity_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0002891I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• abnormal adipose tissue physiology_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005666I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased renal fat pad weight_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009302I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• abnormal brown adipose tissue morphology_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0002971I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• impaired adaptive thermogenesis_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0011049I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• decreased circulating glucose level_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005560I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• decreased oxygen consumption_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005290I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased susceptibility to weight gain_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005455I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• decreased fatty acid oxidation_Ppara<tm1Gonz>/Ppara<tm1Gonz>
  http://metadb.riken.jp/0014172I129S4SvJaePparatm1GonzPparatm1GonzPparatm1Gonz
• decreased fatty acid oxidation_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0014172I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased brown fat cell size_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009119I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased brown adipose tissue amount_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0000005I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• increased inguinal fat pad weight_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009292I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• decreased adipocyte glucose uptake_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0030017I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• impaired lipolysis_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0008033I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul
• decreased circulating insulin level_Pnpla2<tm1.1Hsul>/Pnpla2<tm1.1Hsul>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0002727I129P2OlaHsdC57BL6C57BL6JSJLPnpla2tm11HsulPnpla2tm11HsulTgFabp4cre1Rev0TgFabp4cre1RevPnpla2tm11Hsul