Giorgio. Giannattasio, et.al., The purinergic G protein-coupled receptor 6 inhibits effector T cell activation in allergic pulmonary inflammation., Journal of immunology (Baltimore, Md. : 1950), 2011, 187

http://rdf.ncbi.nlm.nih.gov/pubmed/21724990

Giorgio. Giannattasio, et.al., The purinergic G protein-coupled receptor 6 inhibits effector T cell activation in allergic pulmonary inflammation., Journal of immunology (Baltimore, Md. : 1950), 2011, 187

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• P2ry6<tm1Jabo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304911

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lung inflammation_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001861I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• increased interleukin-13 secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008672I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• increased eosinophil cell number_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005011I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• increased interleukin-13 secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008672B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• increased interleukin-5 secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008702B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• lung inflammation_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001861B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• increased neutrophil cell number_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000219I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• abnormal respiratory mucosa goblet cell morphology_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002281B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• increased interleukin-4 secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008699B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• increased interferon-gamma secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008566I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• decreased IgE level_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002492I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• abnormal respiratory mucosa goblet cell morphology_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002281I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• increased interleukin-5 secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008702I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• increased eosinophil cell number_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005011B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• decreased T cell apoptosis_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0006414I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• increased interferon-gamma secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008566B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• increased T cell proliferation_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005348I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte
• increased neutrophil cell number_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000219B6CgGtROSA26Sortm9creESR1ArteP2ry6tm1JaboP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteP2ry6tm1JaboGtROSA26Sor
• increased interleukin-4 secretion_P2ry6<tm1Jabo>/P2ry6<tm1Jabo>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008699I129C57BL6C57BL6NTacP2ry6tm1JaboP2ry6tm1JaboGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26SorP2ry6tm1JaboGtROSA26Sortm9creESR1Arte

class

http://purl.org/net/cito/citesAsAuthority

• P2ry6<tm1Jabo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304911