Peter. Boross, et.al., The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility., Journal of immunology (Baltimore, Md. : 1950), 2011, 187

http://rdf.ncbi.nlm.nih.gov/pubmed/21724994

Peter. Boross, et.al., The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility., Journal of immunology (Baltimore, Md. : 1950), 2011, 187

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fcgr2b<tm1.2Sjv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427927

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased activated T cell number_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0001829B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• abnormal adaptive immunity_Fcgr2b<tm1.2Sjv>/Fcgr2b<tm1.2Sjv>,Sle16<C57BL/6>/Sle16<C57BL/6>
  http://metadb.riken.jp/0002420IC57BL6FVBNFcgr2btm12SjvFcgr2btm12SjvSle16C57BL6Sle16C57BL6Fcgr2btm12SjvSle16C57BL6
• increased B cell number_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0005014B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• increased anti-single stranded DNA antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0004771I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• premature death_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0002083B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased susceptibility to induced arthritis_Fcgr2b<tm1.2Sjv>/Fcgr2b<tm1.2Sjv>,Sle16<C57BL/6>/Sle16<C57BL/6>
  http://metadb.riken.jp/0003724IC57BL6FVBNFcgr2btm12SjvFcgr2btm12SjvSle16C57BL6Sle16C57BL6Fcgr2btm12SjvSle16C57BL6
• enlarged spleen_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0000691B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased immunoglobulin level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0002461B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased anti-chromatin antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004829B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased anti-double stranded DNA antibody level_Fcgr2b<tm1.2Sjv>/Fcgr2b<+>,X/Yaa
  http://metadb.riken.jp/0004762IC57BL6FVBNSBLeFcgr2btm12SjvFcgr2bXYaaYaaFcgr2bFcgr2btm12Sjv
• glomerular capillary thrombosis_Fcgr2b<tm1.2Sjv>/Fcgr2b<tm1.2Sjv>,Sle16<C57BL/6>/Sle16<C57BL/6>
  http://metadb.riken.jp/0011508IC57BL6FVBNFcgr2btm12SjvFcgr2btm12SjvSle16C57BL6Sle16C57BL6Fcgr2btm12SjvSle16C57BL6
• enlarged spleen_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0000691B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• abnormal adaptive immunity_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0002420B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased anti-double stranded DNA antibody level_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004762B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• albuminuria_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0002871I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• abnormal kidney morphology_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0002135I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• increased anti-chromatin antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0004829I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• increased susceptibility to induced arthritis_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0003724B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased anti-histone antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004796B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased susceptibility to systemic lupus erythematosus_Fcgr2b<tm1.2Sjv>/Fcgr2b<+>,X/Yaa
  http://metadb.riken.jp/0004801IC57BL6FVBNSBLeFcgr2btm12SjvFcgr2bXYaaYaaFcgr2bFcgr2btm12Sjv
• premature death_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0002083I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• abnormal renal glomerulus morphology_Fcgr2b<tm1.2Sjv>/Fcgr2b<tm1.2Sjv>,Sle16<C57BL/6>/Sle16<C57BL/6>
  http://metadb.riken.jp/0005325IC57BL6FVBNFcgr2btm12SjvFcgr2btm12SjvSle16C57BL6Sle16C57BL6Fcgr2btm12SjvSle16C57BL6
• increased spleen weight_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004952B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• premature death_Fcgr2b<tm1.2Sjv>/Fcgr2b<+>,X/Yaa
  http://metadb.riken.jp/0002083IC57BL6FVBNSBLeFcgr2btm12SjvFcgr2bXYaaYaaFcgr2bFcgr2btm12Sjv
• kidney inflammation_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0001859B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased anti-single stranded DNA antibody level_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004771B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• increased anti-chromatin antibody level_Fcgr2b<tm1.2Sjv>/Fcgr2b<+>,X/Yaa
  http://metadb.riken.jp/0004829IC57BL6FVBNSBLeFcgr2btm12SjvFcgr2bXYaaYaaFcgr2bFcgr2btm12Sjv
• increased anti-histone antibody level_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004796B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• increased monocyte cell number_Fcgr2b<tm1.2Sjv>/Fcgr2b<+>,X/Yaa
  http://metadb.riken.jp/0000220IC57BL6FVBNSBLeFcgr2btm12SjvFcgr2bXYaaYaaFcgr2bFcgr2btm12Sjv
• enlarged spleen_Fcgr2b<tm1.2Sjv>/Fcgr2b<+>,X/Yaa
  http://metadb.riken.jp/0000691IC57BL6FVBNSBLeFcgr2btm12SjvFcgr2bXYaaYaaFcgr2bFcgr2btm12Sjv
• increased anti-double stranded DNA antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0004762I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• increased immunoglobulin level_Fcgr2b<tm1.2Sjv>/Fcgr2b<tm1.2Sjv>,Sle16<C57BL/6>/Sle16<C57BL/6>
  http://metadb.riken.jp/0002461IC57BL6FVBNFcgr2btm12SjvFcgr2btm12SjvSle16C57BL6Sle16C57BL6Fcgr2btm12SjvSle16C57BL6
• kidney inflammation_Fcgr2b<tm1.2Sjv>/Fcgr2b<tm1.2Sjv>,Sle16<C57BL/6>/Sle16<C57BL/6>
  http://metadb.riken.jp/0001859IC57BL6FVBNFcgr2btm12SjvFcgr2btm12SjvSle16C57BL6Sle16C57BL6Fcgr2btm12SjvSle16C57BL6
• increased anti-single stranded DNA antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004771B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased spleen weight_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004952B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased anti-histone antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0004796I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• increased susceptibility to systemic lupus erythematosus_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0004801I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• increased anti-chromatin antibody level_Fcgr3<tm1Sjv>/Fcgr3<tm1Sjv>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004829B6129P2Fcgr3tm1SjvFcgr3tm1SjvFcgr3tm1SjvSle21129P2OlaSle21129P2OlaFcgr3tm1SjvSle21129P2Ola
• increased spleen weight_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0004952I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• no abnormal phenotype detected_Fcgr2b<tm1.1Sjv>/Fcgr2b<tm1.1Sjv>
  http://metadb.riken.jp/0002169IC57BL6FVBNFcgr2btm11SjvFcgr2btm11SjvFcgr2btm11Sjv
• albuminuria_Fcgr2b<tm1.2Sjv>/Fcgr2b<tm1.2Sjv>,Sle16<C57BL/6>/Sle16<C57BL/6>
  http://metadb.riken.jp/0002871IC57BL6FVBNFcgr2btm12SjvFcgr2btm12SjvSle16C57BL6Sle16C57BL6Fcgr2btm12SjvSle16C57BL6
• enlarged spleen_Fcgr2b<tm1Ttk>/Fcgr2b<tm1.2Sjv>,Sle21<129P2/Ola>/Sle21<C57BL/6>
  http://metadb.riken.jp/0000691I129P2Ola129S4SvJaeC57BL6FVBNFcgr2btm1TtkFcgr2btm12SjvSle21129P2OlaSle21C57BL6Fcgr2btm1TtkSle21C57BL6Sle21129P2OlaFcgr2btm12Sjv
• increased autoantibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0003725B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased anti-double stranded DNA antibody level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004762B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• glomerular capillary thrombosis_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0011508B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• albuminuria_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0002871B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• abnormal renal glomerulus morphology_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0005325B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased susceptibility to systemic lupus erythematosus_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0004801B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• increased IgG2a level_Fcgr2b<tm1Ttk>/Fcgr2b<tm1Ttk>,Sle21<129P2/Ola>/Sle21<129P2/Ola>
  http://metadb.riken.jp/0008500B6129S4Fcgr2btm1TtkFcgr2btm1TtkFcgr2btm1TtkSle21129P2OlaSle21129P2OlaSle21129P2OlaFcgr2btm1Ttk
• abnormal kidney morphology_Fcgr2b<tm1.2Sjv>/Fcgr2b<+>,X/Yaa
  http://metadb.riken.jp/0002135IC57BL6FVBNSBLeFcgr2btm12SjvFcgr2bXYaaYaaFcgr2bFcgr2btm12Sjv

class

http://purl.org/net/cito/citesAsAuthority

• Fcgr2b<tm1.2Sjv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427927