Lei. Huang, et.al., The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21730163

Lei. Huang, et.al., The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mdm4<tm1Zmy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5141749

class

http://purl.org/net/cito/citesAsAuthority

• Mdm4<tm1Zmy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5141749

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased embryonic tissue cell apoptosis_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>
  http://metadb.riken.jp/0013504I129C57BL6Mdm4tm1ZmyMdm4tm1ZmyMdm4tm1Zmy
• absent somites_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>
  http://metadb.riken.jp/0006386I129C57BL6Mdm4tm1ZmyMdm4tm1ZmyMdm4tm1Zmy
• abnormal heart development_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>
  http://metadb.riken.jp/0000267I129C57BL6Mdm4tm1ZmyMdm4tm1ZmyMdm4tm1Zmy
• abnormal embryonic neuroepithelium morphology_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>
  http://metadb.riken.jp/0004261I129C57BL6Mdm4tm1ZmyMdm4tm1ZmyMdm4tm1Zmy
• embryonic lethality during organogenesis, complete penetrance_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>
  http://metadb.riken.jp/0011098I129C57BL6Mdm4tm1ZmyMdm4tm1ZmyMdm4tm1Zmy
• no abnormal phenotype detected_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002169I129S2SvPasC57BL6Mdm4tm1ZmyMdm4tm1ZmyTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjMdm4tm1Zmy
• decreased embryo size_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>
  http://metadb.riken.jp/0001698I129C57BL6Mdm4tm1ZmyMdm4tm1ZmyMdm4tm1Zmy
• decreased cell proliferation_Mdm4<tm1Zmy>/Mdm4<tm1Zmy>
  http://metadb.riken.jp/0000352I129C57BL6Mdm4tm1ZmyMdm4tm1ZmyMdm4tm1Zmy