Takuya. Yagi, et.al., N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress., Human molecular genetics, 2011, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/21750110

Takuya. Yagi, et.al., N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress., Human molecular genetics, 2011, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-BSCL2*N88S)#Dit
  http://metadb.riken.jp/db/mgi_rdf/MGI:5295199

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal motor capabilities/coordination/movement_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0002066IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• axon degeneration_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0005405IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• short stride length_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0001407IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• paralysis_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• decreased survivor rate_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0008770IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• premature death_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• abnormal axonal transport_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0004768IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• abnormal nervous system morphology_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0003632IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• muscular atrophy_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0002269IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• impaired coordination_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0001405IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• increased endoplasmic reticulum stress_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0020354IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• astrocytosis_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• gliosis_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0002183IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• abnormal gait_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0001406IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• limb grasping_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0001513IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• decreased grip strength_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0010053IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit
• decreased body weight_Tg(Thy1-BSCL2*N88S)#Dit/0
  http://metadb.riken.jp/0001262IC57BL6DBA2TgThy1BSCL2N88SDit0TgThy1BSCL2N88SDit

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-BSCL2*N88S)#Dit
  http://metadb.riken.jp/db/mgi_rdf/MGI:5295199

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;B6D2-Tg(Thy1-BSCL2*N88S)1
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC05350

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]