Rosa M. Guzzo, et.al., Persistent expression of Twist1 in chondrocytes causes growth plate abnormalities and dwarfism in mice., The International journal of developmental biology, 2011, 55

http://rdf.ncbi.nlm.nih.gov/pubmed/21769775

Rosa M. Guzzo, et.al., Persistent expression of Twist1 in chondrocytes causes growth plate abnormalities and dwarfism in mice., The International journal of developmental biology, 2011, 55

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• short limbs_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000547IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• abnormal long bone epiphyseal plate proliferative zone_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003662IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• decreased trabecular bone volume_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0010879IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• increased width of hypertrophic chondrocyte zone_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003408IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• decreased bone trabecula number_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0010869IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• decreased trabecular bone thickness_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0009346IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• decreased body weight_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0001262IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• abnormal long bone epiphyseal plate morphology_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003055IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• decreased body size_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0001265IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr
• abnormal ossification involved in bone maturation_Tg(CAG-cat,-Twist1)1Dbsp/0,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0011722IC57BL6FVBSJLTgCAGcatTwist11Dbsp0TgCol2a1cre1Bhr0TgCAGcatTwist11DbspTgCol2a1cre1Bhr