Zhe. Li, et.al., Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies., Blood, 2011, 118

http://rdf.ncbi.nlm.nih.gov/pubmed/21803851

Zhe. Li, et.al., Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies., Blood, 2011, 118

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tet2<tm1.2Mjxu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5301344
• Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5301343

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased leukocyte cell number_Tet2<tm1.1Mjxu>/Tet2<+>
  http://metadb.riken.jp/0000218I129C57BL6Tet2tm11MjxuTet2Tet2tm11MjxuTet2
• increased hemoglobin content_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0005564I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• increased chronic myelocytic leukemia incidence_Tet2<tm1.1Mjxu>/Tet2<+>
  http://metadb.riken.jp/0005481I129C57BL6Tet2tm11MjxuTet2Tet2tm11MjxuTet2
• increased leukemia incidence_Tet2<tm1.1Mjxu>/Tet2<+>
  http://metadb.riken.jp/0002026I129C57BL6Tet2tm11MjxuTet2Tet2tm11MjxuTet2
• increased bone marrow cell number_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0000321I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• enlarged liver_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0000599I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• premature death_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0002083I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• enlarged spleen_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0000691I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• increased erythrocyte cell number_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0003131I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• premature death_Tet2<tm1.1Mjxu>/Tet2<+>
  http://metadb.riken.jp/0002083I129C57BL6Tet2tm11MjxuTet2Tet2tm11MjxuTet2
• myeloid hyperplasia_Tet2<tm1.1Mjxu>/Tet2<+>
  http://metadb.riken.jp/0010373I129C57BL6Tet2tm11MjxuTet2Tet2tm11MjxuTet2
• anemia_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0001577I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• abnormal common myeloid progenitor cell morphology_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0006410I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• myeloid hyperplasia_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0010373I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• increased monocyte cell number_Tet2<tm1.1Mjxu>/Tet2<+>
  http://metadb.riken.jp/0000220I129C57BL6Tet2tm11MjxuTet2Tet2tm11MjxuTet2
• increased leukemia incidence_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0002026I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• enlarged spleen_Tet2<tm1.1Mjxu>/Tet2<+>
  http://metadb.riken.jp/0000691I129C57BL6Tet2tm11MjxuTet2Tet2tm11MjxuTet2
• increased neutrophil cell number_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0000219I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• increased leukocyte cell number_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0000218I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• increased chronic myelocytic leukemia incidence_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0005481I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• increased hematopoietic stem cell number_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0004809I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• increased monocyte cell number_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0000220I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu
• abnormal hematopoietic stem cell physiology_Tet2<tm1.1Mjxu>/Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/0010763I129C57BL6Tet2tm11MjxuTet2tm11MjxuTet2tm11Mjxu

class

http://purl.org/net/cito/citesAsAuthority

• Tet2<tm1.2Mjxu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5301344
• Tet2<tm1.1Mjxu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5301343