Makiko. Kawaguchi, et.al., Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity., The American journal of pathology, 2011, 179

http://rdf.ncbi.nlm.nih.gov/pubmed/21840293

Makiko. Kawaguchi, et.al., Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity., The American journal of pathology, 2011, 179

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Spint1<tm2.1Hk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304850

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal defecation_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003866IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• abnormal large intestine crypts of Lieberkuhn morphology_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0004842IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• abnormal enterocyte proliferation_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008883IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• increased sensitivity to xenobiotic induced morbidity/mortality_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0009766IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• abnormal intestine physiology_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0010155IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• intestinal ulcer_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000512IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• increased susceptibility to weight loss_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0010180IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• small cecum_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0009477IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• increased susceptibility to induced colitis_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008537IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• increased enterocyte apoptosis_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008885IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum
• diarrhea_Spint1<tm2.1Hk>/Spint1<tm2.1Hk>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0005036IC57BL6C57BL6JSJLSpint1tm21HkSpint1tm21HkTgVil1cre997Gum0Spint1tm21HkTgVil1cre997Gum

class

http://purl.org/net/cito/citesAsAuthority

• Spint1<tm2.1Hk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304850