Guenter. Haemmerle, et.al., ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1., Nature medicine, 2011, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/21857651

Guenter. Haemmerle, et.al., ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1., Nature medicine, 2011, 17

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pnpla2<tm1Eek>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5294351
• Tg(Myh6-Pnpla2)94Biat
  http://metadb.riken.jp/db/mgi_rdf/MGI:5294356

class

http://purl.org/net/cito/citesAsAuthority

• Pnpla2<tm1Eek>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5294351
• Tg(Myh6-Pnpla2)94Biat
  http://metadb.riken.jp/db/mgi_rdf/MGI:5294356

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased brown adipose tissue amount_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>,Tg(Myh6-Pnpla2)94Biat/0
  http://metadb.riken.jp/0000005I129P2OlaHsdC57BL6DBA2Pnpla2tm1RzePnpla2tm1RzeTgMyh6Pnpla294Biat0TgMyh6Pnpla294BiatPnpla2tm1Rze
• increased brown adipose tissue amount_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0000005I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased white adipose tissue amount_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>,Tg(Myh6-Pnpla2)94Biat/0
  http://metadb.riken.jp/0000008I129P2OlaHsdC57BL6DBA2Pnpla2tm1RzePnpla2tm1RzeTgMyh6Pnpla294Biat0TgMyh6Pnpla294BiatPnpla2tm1Rze
• increased white adipose tissue amount_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0000008I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• abnormal myocardial fiber morphology_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0000278I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• cardiac hypertrophy_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0001625I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
他23件を見る
• premature death_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0002083I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• abnormal cardiovascular system morphology_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0002127I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased heart rate_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0002626I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• decreased circulating triglyceride level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>,Tg(Myh6-Pnpla2)94Biat/0
  http://metadb.riken.jp/0002644I129P2OlaHsdC57BL6DBA2Pnpla2tm1RzePnpla2tm1RzeTgMyh6Pnpla294Biat0TgMyh6Pnpla294BiatPnpla2tm1Rze
• decreased circulating triglyceride level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0002644I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• decreased circulating free fatty acid level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>,Tg(Myh6-Pnpla2)94Biat/0
  http://metadb.riken.jp/0002702I129P2OlaHsdC57BL6DBA2Pnpla2tm1RzePnpla2tm1RzeTgMyh6Pnpla294Biat0TgMyh6Pnpla294BiatPnpla2tm1Rze
• decreased circulating free fatty acid level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0002702I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased heart weight_Pnpla2<tm1Eek>/Pnpla2<tm1Eek>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002833I129SFVBNPnpla2tm1EekPnpla2tm1EekTgCkmmcre5Khn0TgCkmmcre5KhnPnpla2tm1Eek
• increased left ventricle weight_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0003915I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• abnormal respiratory quotient_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0004129I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• abnormal myocardial fiber physiology_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0004215I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• abnormal metabolism_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0005266I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased fatty acid level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0005281I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• decreased oxygen consumption_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0005290I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• abnormal heart ventricle morphology_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0005294I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased triglyceride level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0005317I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased triglyceride level_Pnpla2<tm1Eek>/Pnpla2<tm1Eek>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005317I129SFVBNPnpla2tm1EekPnpla2tm1EekTgCkmmcre5Khn0TgCkmmcre5KhnPnpla2tm1Eek
• decreased ventricle muscle contractility_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0005598I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• abnormal mitochondrion morphology_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0006035I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased liver triglyceride level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0009355I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased respiratory quotient_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0010378I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• thick interventricular septum_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0010724I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze
• increased cardiac muscle glycogen level_Pnpla2<tm1Rze>/Pnpla2<tm1Rze>
  http://metadb.riken.jp/0014071I129P2OlaHsdPnpla2tm1RzePnpla2tm1RzePnpla2tm1Rze