Song. Lu, et.al., Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood., Neurobiology of disease, 2012, 45

http://rdf.ncbi.nlm.nih.gov/pubmed/21871565

Song. Lu, et.al., Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood., Neurobiology of disease, 2012, 45

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pdss2<tm1Jdhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304514
• Pdss2<tm1.1Jdhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304516
• Pdss2<tm1.2Jdhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304520

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• short mandible_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000088I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• cleft palate_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000111I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal cell morphology_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000358I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal skeletal muscle morphology_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000759I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal cerebellum morphology_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000849I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• cerebellum hypoplasia_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000851I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
他28件を見る
• small cerebellum_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000852I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal cerebellum development_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000854I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal cerebellar foliation_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000857I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• cerebellum vermis hypoplasia_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0000866I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• Purkinje cell degeneration_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0000876I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• decreased Purkinje cell number_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0000880I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• ataxia_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0001393I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• abnormal gait_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0001406I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• short stride length_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0001407I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• abnormal motor coordination/ balance_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0001516I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• impaired balance_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0001525I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• respiratory distress_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0001954I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• micrognathia_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0002639I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• dysphagia_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0003158I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• increased neuron apoptosis_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pcp2-cre)3555Jdhu/0
  http://metadb.riken.jp/0003203I129C3HHeNCrMMTVC57BL6NFVBNGtROSA26Sortm1SorGtROSA26SorPdss2tm11JdhuPdss2tm12JdhuTgPcp2cre3555Jdhu0Pdss2tm11JdhuPdss2tm12JdhuGtROSA26SorTgPcp2cre3555JdhuGtROSA26Sortm1Sor
• increased neuron apoptosis_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0003203I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal radial glial cell morphology_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0003648I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal embryonic/fetal subventricular zone morphology_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0004274I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal palatine bone horizontal plate morphology_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0004537I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal mitochondrion morphology_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0006035I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• absent gastric milk in neonates_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0009546I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• absent Purkinje cell layer_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0009718I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• abnormal Purkinje cell migration_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0010008I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• postnatal lethality, complete penetrance_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0011085I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• embryonic lethality during organogenesis, complete penetrance_Pdss2<tm1.2Jdhu>/Pdss2<tm1.2Jdhu>
  http://metadb.riken.jp/0011098I129C57BL6NFVBNPdss2tm12JdhuPdss2tm12JdhuPdss2tm12Jdhu
• decreased midbrain size_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0012089I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• midbrain hypoplasia_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0012090I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu
• decreased radial glial cell number_Pdss2<tm1.1Jdhu>/Pdss2<tm1.2Jdhu>,Tg(Pax2-cre)1Akg/0
  http://metadb.riken.jp/0020388I129C57BL6NFVBNPdss2tm11JdhuPdss2tm12JdhuTgPax2cre1Akg0TgPax2cre1AkgPdss2tm12JdhuPdss2tm11Jdhu

class

http://purl.org/net/cito/citesAsAuthority

• Pdss2<tm1Jdhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304514
• Pdss2<tm1.1Jdhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304516
• Pdss2<tm1.2Jdhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304520