Yukitomo. Arao, et.al., Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21873215

Yukitomo. Arao, et.al., Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Esr1<tm3.1Ksk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5301452

class

http://purl.org/net/cito/citesAsAuthority

• Esr1<tm3.1Ksk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5301452

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal ovarian follicle morphology_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0001131I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• abnormal mammary gland development_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0000628I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• uterus cysts_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0009082I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• increased luteinizing hormone level_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0005133I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• absent corpus luteum_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0001134I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• small uterus_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0002637I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• uterus hypoplasia_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0001121I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• abnormal response/metabolism to endogenous compounds_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0003638I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• absent estrous cycle_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0009009I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• decreased endometrial gland number_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0009096I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• decreased primordial ovarian follicle number_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0011121I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk
• increased circulating estradiol level_Esr1<tm3.1Ksk>/Esr1<tm3.1Ksk>
  http://metadb.riken.jp/0005182I129S6SvEvTacC57BL6Esr1tm31KskEsr1tm31KskEsr1tm31Ksk